Isolation and Confirmation of the Proposed Cleistanthol Biogentic Link from Croton insularis

Isolation and Confirmation of the Proposed Cleistanthol Biogentic Link from Croton insularis

The proposed cleistanthol biosynthetic intermediate en route to spruceanol, and other related family members, was isolated for the first time from Croton insularis, confirming the Jacobs−Reynolds hypothesis. Anticancer evaluation of the new isolates and their aerial oxidation products is also report...

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Veröffentlicht in:Organic letters 2011-03, Vol.13 (5), p.1032-1035
Hauptverfasser: Maslovskaya, Lidia A, Savchenko, Andrei I, Gordon, Victoria A, Reddell, Paul W, Pierce, Carly J, Parsons, Peter G, Williams, Craig M
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Sprache:eng
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Croton - chemistry
Diterpenes - chemical synthesis
Diterpenes - chemistry
Molecular Structure
Oxidation-Reduction
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container_end_page 1035
container_issue 5
container_start_page 1032
container_title Organic letters
container_volume 13
creator Maslovskaya, Lidia A
Savchenko, Andrei I
Gordon, Victoria A
Reddell, Paul W
Pierce, Carly J
Parsons, Peter G
Williams, Craig M
description The proposed cleistanthol biosynthetic intermediate en route to spruceanol, and other related family members, was isolated for the first time from Croton insularis, confirming the Jacobs−Reynolds hypothesis. Anticancer evaluation of the new isolates and their aerial oxidation products is also reported.
doi_str_mv 10.1021/ol103083m
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source American Chemical Society; MEDLINE
subjects Croton - chemistry
Diterpenes - chemical synthesis
Diterpenes - chemistry
Molecular Structure
Oxidation-Reduction
title Isolation and Confirmation of the Proposed Cleistanthol Biogentic Link from Croton insularis
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