Isolation and Confirmation of the Proposed Cleistanthol Biogentic Link from Croton insularis

Isolation and Confirmation of the Proposed Cleistanthol Biogentic Link from Croton insularis

The proposed cleistanthol biosynthetic intermediate en route to spruceanol, and other related family members, was isolated for the first time from Croton insularis, confirming the Jacobs−Reynolds hypothesis. Anticancer evaluation of the new isolates and their aerial oxidation products is also report...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Organic letters 2011-03, Vol.13 (5), p.1032-1035
Hauptverfasser: Maslovskaya, Lidia A, Savchenko, Andrei I, Gordon, Victoria A, Reddell, Paul W, Pierce, Carly J, Parsons, Peter G, Williams, Craig M
Format: Artikel
Sprache:eng
Schlagworte:
Croton - chemistry
Diterpenes - chemical synthesis
Diterpenes - chemistry
Molecular Structure
Oxidation-Reduction
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The proposed cleistanthol biosynthetic intermediate en route to spruceanol, and other related family members, was isolated for the first time from Croton insularis, confirming the Jacobs−Reynolds hypothesis. Anticancer evaluation of the new isolates and their aerial oxidation products is also reported.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol103083m