Molecular determinants of immunogenic cell death elicited by anticancer chemotherapy

The success of some chemo- and radiotherapeutic regimens relies on the induction of immunogenic tumor cell death and on the induction of an anticancer immune response. Cells succumbing to immunogenic cell death undergo specific changes in their surface characteristics and release pro-immunogenic fac...

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Veröffentlicht in:	Cancer and metastasis reviews 2011-03, Vol.30 (1), p.61-69
Hauptverfasser:	Kepp, Oliver, Galluzzi, Lorenzo, Martins, Isabelle, Schlemmer, Frederic, Adjemian, Sandy, Michaud, Mickael, Sukkurwala, Abdul Qader, Menger, Laurie, Zitvogel, Laurence, Kroemer, Guido
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen (tumor-associated) Antigen-presenting cells Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use ATP B cells Biochemistry Biomedical and Life Sciences Biomedicine Calreticulin Cancer Cancer Research Cell death Cell Death - drug effects Cell Death - immunology Chemotherapy Cytotoxicity Dendritic cells Endoplasmic reticulum HMGB1 protein Humans Immune response Immunogenicity Lymphocytes T Metabolites Metastases Microenvironments Neoplasms - drug therapy Neoplasms - immunology Oncology Protein binding Signal Transduction - drug effects Signal Transduction - immunology Stem cells T cells Transplantation Tumor antigens Tumor cells Tumors Vincristine
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