Inhibition of Neuroinflammation Prevents Injury to the Serotonergic Network After Hypoxia-Ischemia in the Immature Rat Brain

The phenotypic identities and characterization of neural networks disrupted after neonatal hypoxia-ischemia (HI) in the preterm brain remain to be elucidated. Interruption of the central serotonergic (5-hydroxytryptamine [5-HT]) system can lead to numerous functional deficits, many of which match th...

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Veröffentlicht in:	Journal of neuropathology and experimental neurology 2011-01, Vol.70 (1), p.23-35
Hauptverfasser:	Wixey, Julie A, Reinebrant, Hanna E, Buller, Kathryn M
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcoholism and acute alcohol poisoning Animals Animals, Newborn Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Biological and medical sciences Female Hypoxia-Ischemia, Brain - metabolism Hypoxia-Ischemia, Brain - pathology Hypoxia-Ischemia, Brain - prevention & control Inflammation - metabolism Inflammation - pathology Inflammation - prevention & control Inflammation Mediators - administration & dosage Inflammation Mediators - therapeutic use Medical sciences Minocycline - therapeutic use Nerve Net - drug effects Nerve Net - metabolism Nerve Net - pathology Neurology Prosencephalon - drug effects Prosencephalon - growth & development Prosencephalon - metabolism Random Allocation Rats Rats, Sprague-Dawley RNA-Binding Proteins - physiology Serotonin - physiology Toxicology
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