Controlled Delivery of Transforming Growth Factor beta 1 by Self-Assembling Peptide Hydrogels Induces Chondrogenesis of Bone Marrow Stromal Cells and Modulates Smad2/3 Signaling

Self-assembling peptide hydrogels were modified to deliver transforming growth factor beta 1 (TGF- beta 1) to encapsulated bone-marrow-derived stromal cells (BMSCs) for cartilage tissue engineering applications using two different approaches: (i) biotin-streptavidin tethering; (ii) adsorption to the...

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Veröffentlicht in:Tissue engineering. Part A 2011-01, Vol.17 (1-2), p.83-92
Hauptverfasser: Kopesky, P W, Vanderploeg, E J, Kisiday, J D, Frisbie, D D, Sandy, J D, Grodzinsky, A J
Format: Artikel
Sprache:eng
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