Lymphadenopathy and Expression of Nodal Mast Cells and Eosinophils in the Myiasis by Human Bot Fly
Wistar rats (Rattus norvegicus) infested with Dermatobia hominis (L. Jr., 1781) had their axillary lymph nodes removed and histopathologically processed. Follicular hyperplasia in the germinal center was noted from 2 d postinfestation (dpi), exhibiting a high number of centerblasts, mitotic and apop...
Gespeichert in:
| Veröffentlicht in: | Journal of medical entomology 2009-11, Vol.46 (6), p.1514-1518 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1518 |
|---|---|
| container_issue | 6 |
| container_start_page | 1514 |
| container_title | Journal of medical entomology |
| container_volume | 46 |
| creator | Cardoso, P.J.G. Leite, V.H.R. Leite, L.H.R. Leite, A.C.R. |
| description | Wistar rats (Rattus norvegicus) infested with Dermatobia hominis (L. Jr., 1781) had their axillary lymph nodes removed and histopathologically processed. Follicular hyperplasia in the germinal center was noted from 2 d postinfestation (dpi), exhibiting a high number of centerblasts, mitotic and apoptotic cells, and a thin parafollicular area. The paracortex showed hyperplasia rich in dendritic cells, immunoblasts, and endothelial venules, with diapedesis seen from 4 dpi onward. Hyperplasia of the medullar sinus also was first observed at this point, as well as dilated lymphatic sinus, lymph, macrophages, neutrophils, mast cells, and eosinophils. Medullar strings were expanded and filled with immunoblasts, mitotic cells, and plasmocytes. Lymphadenitis was not observed. The expression of mast cells was similar for both myiasis-affected and control rats but increased significantly (mastocytosis) at 7 and 15 d postlarval emergence (dple). Eosinophilia was observed at 4, 10, 15, 20, and 28 dpi as well as at 2, 7, and 15 dple, particularly on the last three observations of dpi and the earliest dple. This experimental approach allowed progressive tissue reactions in the lymph nodes to be monitored during myiasis, particularly those involving mast cells and eosinophils. These reactions abated and complete repair was observed at 60 dple. |
| doi_str_mv | 10.1603/033.046.0640 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_853481915</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A535150775</galeid><sourcerecordid>A535150775</sourcerecordid><originalsourceid>FETCH-LOGICAL-b520t-3515d8cfc9cecd39b95d46002740409e78df549a8e456e462a764c445683fbbc3</originalsourceid><addsrcrecordid>eNqNkU1v1DAQhi0EotvCjTP4gpAqsow_Yx_LqqVIWzhAz5Hj2F2jJE7jrET-PY6yghsgH6yxnhm94wehVwS2RAL7AIxtgcstSA5P0IZopgqqqXqKNgCUFlQocYbOU_oBAIpw_RydEa0llCA3qN7P3XAwjevjYKbDjE3f4Oufw-hSCrHH0eMvsTEtvjNpwjvXtmlFYgq55RByHXo8HRy-m4NJIeF6xrfHzvT4Y5zwTTu_QM-8aZN7ebov0P3N9ffdbbH_-unz7mpf1ILCVDBBRKOst9o62zBda9FwmVcoOXDQrlSNF1wb5biQjktqSsktz4Vivq4tu0Dv1rnDGB-PLk1VF5LNiU3v4jFVSjCuiCbiP0jCS5I_7p9kyVh2QDRkcruSD6Z1Veh9nEZj82lcF2zsnQ_5_Uosa0JZLiHerw12jCmNzlfDGDozzhWBajFbZbNVNlstZjP--pTkWHeu-QOfVGbg7QkwyZrWj6a3If3mKCUUhFwGvVk5b2JlHsbM3H-jQBiQkiohSSYuV6IOMQf_e65fjju-Lw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>733603190</pqid></control><display><type>article</type><title>Lymphadenopathy and Expression of Nodal Mast Cells and Eosinophils in the Myiasis by Human Bot Fly</title><source>Oxford University Press Journals All Titles (1996-Current)</source><source>MEDLINE</source><source>BioOne Complete</source><creator>Cardoso, P.J.G. ; Leite, V.H.R. ; Leite, L.H.R. ; Leite, A.C.R.</creator><creatorcontrib>Cardoso, P.J.G. ; Leite, V.H.R. ; Leite, L.H.R. ; Leite, A.C.R.</creatorcontrib><description>Wistar rats (Rattus norvegicus) infested with Dermatobia hominis (L. Jr., 1781) had their axillary lymph nodes removed and histopathologically processed. Follicular hyperplasia in the germinal center was noted from 2 d postinfestation (dpi), exhibiting a high number of centerblasts, mitotic and apoptotic cells, and a thin parafollicular area. The paracortex showed hyperplasia rich in dendritic cells, immunoblasts, and endothelial venules, with diapedesis seen from 4 dpi onward. Hyperplasia of the medullar sinus also was first observed at this point, as well as dilated lymphatic sinus, lymph, macrophages, neutrophils, mast cells, and eosinophils. Medullar strings were expanded and filled with immunoblasts, mitotic cells, and plasmocytes. Lymphadenitis was not observed. The expression of mast cells was similar for both myiasis-affected and control rats but increased significantly (mastocytosis) at 7 and 15 d postlarval emergence (dple). Eosinophilia was observed at 4, 10, 15, 20, and 28 dpi as well as at 2, 7, and 15 dple, particularly on the last three observations of dpi and the earliest dple. This experimental approach allowed progressive tissue reactions in the lymph nodes to be monitored during myiasis, particularly those involving mast cells and eosinophils. These reactions abated and complete repair was observed at 60 dple.</description><identifier>ISSN: 0022-2585</identifier><identifier>EISSN: 1938-2928</identifier><identifier>EISSN: 0022-2585</identifier><identifier>DOI: 10.1603/033.046.0640</identifier><identifier>PMID: 19960706</identifier><identifier>CODEN: JMENA6</identifier><language>eng</language><publisher>Lanham, MD: Entomological Society of America</publisher><subject>animal models ; Animals ; Apoptosis ; Biological and medical sciences ; bot flies ; Dendritic cells ; Dermatobia hominis ; diapedesis ; Diptera - growth & development ; DIRECT INJURY, MYIASIS, FORENSICS ; eosinophil ; Eosinophilia ; eosinophils ; Eosinophils - immunology ; Eosinophils - pathology ; Fundamental and applied biological sciences. Psychology ; Germinal centers ; Hyperplasia ; immune response ; Leukocytes (eosinophilic) ; Leukocytes (neutrophilic) ; Lymph nodes ; Lymph Nodes - immunology ; Lymph Nodes - pathology ; Lymphadenitis ; Lymphadenopathy ; lymphatic diseases ; Lymphatic Diseases - immunology ; Lymphatic Diseases - parasitology ; Macrophages ; Male ; mast cell ; Mast cells ; Mast Cells - immunology ; Mast Cells - pathology ; Mastocytosis ; Medically important nuisances and vectors, pests of stored products and materials: population survey and control ; Myiasis ; Myiasis - immunology ; Myiasis - pathology ; Rats ; Rats, Wistar ; Rattus norvegicus ; Sinus ; Vectors. Intermediate hosts</subject><ispartof>Journal of medical entomology, 2009-11, Vol.46 (6), p.1514-1518</ispartof><rights>2009 Entomological Society of America</rights><rights>2015 INIST-CNRS</rights><rights>COPYRIGHT 2009 Oxford University Press</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b520t-3515d8cfc9cecd39b95d46002740409e78df549a8e456e462a764c445683fbbc3</citedby><cites>FETCH-LOGICAL-b520t-3515d8cfc9cecd39b95d46002740409e78df549a8e456e462a764c445683fbbc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://bioone.org/doi/pdf/10.1603/033.046.0640$$EPDF$$P50$$Gbioone$$H</linktopdf><link.rule.ids>314,776,780,26955,27901,27902,52338</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22120560$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19960706$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cardoso, P.J.G.</creatorcontrib><creatorcontrib>Leite, V.H.R.</creatorcontrib><creatorcontrib>Leite, L.H.R.</creatorcontrib><creatorcontrib>Leite, A.C.R.</creatorcontrib><title>Lymphadenopathy and Expression of Nodal Mast Cells and Eosinophils in the Myiasis by Human Bot Fly</title><title>Journal of medical entomology</title><addtitle>J Med Entomol</addtitle><description>Wistar rats (Rattus norvegicus) infested with Dermatobia hominis (L. Jr., 1781) had their axillary lymph nodes removed and histopathologically processed. Follicular hyperplasia in the germinal center was noted from 2 d postinfestation (dpi), exhibiting a high number of centerblasts, mitotic and apoptotic cells, and a thin parafollicular area. The paracortex showed hyperplasia rich in dendritic cells, immunoblasts, and endothelial venules, with diapedesis seen from 4 dpi onward. Hyperplasia of the medullar sinus also was first observed at this point, as well as dilated lymphatic sinus, lymph, macrophages, neutrophils, mast cells, and eosinophils. Medullar strings were expanded and filled with immunoblasts, mitotic cells, and plasmocytes. Lymphadenitis was not observed. The expression of mast cells was similar for both myiasis-affected and control rats but increased significantly (mastocytosis) at 7 and 15 d postlarval emergence (dple). Eosinophilia was observed at 4, 10, 15, 20, and 28 dpi as well as at 2, 7, and 15 dple, particularly on the last three observations of dpi and the earliest dple. This experimental approach allowed progressive tissue reactions in the lymph nodes to be monitored during myiasis, particularly those involving mast cells and eosinophils. These reactions abated and complete repair was observed at 60 dple.</description><subject>animal models</subject><subject>Animals</subject><subject>Apoptosis</subject><subject>Biological and medical sciences</subject><subject>bot flies</subject><subject>Dendritic cells</subject><subject>Dermatobia hominis</subject><subject>diapedesis</subject><subject>Diptera - growth & development</subject><subject>DIRECT INJURY, MYIASIS, FORENSICS</subject><subject>eosinophil</subject><subject>Eosinophilia</subject><subject>eosinophils</subject><subject>Eosinophils - immunology</subject><subject>Eosinophils - pathology</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Germinal centers</subject><subject>Hyperplasia</subject><subject>immune response</subject><subject>Leukocytes (eosinophilic)</subject><subject>Leukocytes (neutrophilic)</subject><subject>Lymph nodes</subject><subject>Lymph Nodes - immunology</subject><subject>Lymph Nodes - pathology</subject><subject>Lymphadenitis</subject><subject>Lymphadenopathy</subject><subject>lymphatic diseases</subject><subject>Lymphatic Diseases - immunology</subject><subject>Lymphatic Diseases - parasitology</subject><subject>Macrophages</subject><subject>Male</subject><subject>mast cell</subject><subject>Mast cells</subject><subject>Mast Cells - immunology</subject><subject>Mast Cells - pathology</subject><subject>Mastocytosis</subject><subject>Medically important nuisances and vectors, pests of stored products and materials: population survey and control</subject><subject>Myiasis</subject><subject>Myiasis - immunology</subject><subject>Myiasis - pathology</subject><subject>Rats</subject><subject>Rats, Wistar</subject><subject>Rattus norvegicus</subject><subject>Sinus</subject><subject>Vectors. Intermediate hosts</subject><issn>0022-2585</issn><issn>1938-2928</issn><issn>0022-2585</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU1v1DAQhi0EotvCjTP4gpAqsow_Yx_LqqVIWzhAz5Hj2F2jJE7jrET-PY6yghsgH6yxnhm94wehVwS2RAL7AIxtgcstSA5P0IZopgqqqXqKNgCUFlQocYbOU_oBAIpw_RydEa0llCA3qN7P3XAwjevjYKbDjE3f4Oufw-hSCrHH0eMvsTEtvjNpwjvXtmlFYgq55RByHXo8HRy-m4NJIeF6xrfHzvT4Y5zwTTu_QM-8aZN7ebov0P3N9ffdbbH_-unz7mpf1ILCVDBBRKOst9o62zBda9FwmVcoOXDQrlSNF1wb5biQjktqSsktz4Vivq4tu0Dv1rnDGB-PLk1VF5LNiU3v4jFVSjCuiCbiP0jCS5I_7p9kyVh2QDRkcruSD6Z1Veh9nEZj82lcF2zsnQ_5_Uosa0JZLiHerw12jCmNzlfDGDozzhWBajFbZbNVNlstZjP--pTkWHeu-QOfVGbg7QkwyZrWj6a3If3mKCUUhFwGvVk5b2JlHsbM3H-jQBiQkiohSSYuV6IOMQf_e65fjju-Lw</recordid><startdate>20091101</startdate><enddate>20091101</enddate><creator>Cardoso, P.J.G.</creator><creator>Leite, V.H.R.</creator><creator>Leite, L.H.R.</creator><creator>Leite, A.C.R.</creator><general>Entomological Society of America</general><general>Oxford University Press</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7SS</scope></search><sort><creationdate>20091101</creationdate><title>Lymphadenopathy and Expression of Nodal Mast Cells and Eosinophils in the Myiasis by Human Bot Fly</title><author>Cardoso, P.J.G. ; Leite, V.H.R. ; Leite, L.H.R. ; Leite, A.C.R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b520t-3515d8cfc9cecd39b95d46002740409e78df549a8e456e462a764c445683fbbc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>animal models</topic><topic>Animals</topic><topic>Apoptosis</topic><topic>Biological and medical sciences</topic><topic>bot flies</topic><topic>Dendritic cells</topic><topic>Dermatobia hominis</topic><topic>diapedesis</topic><topic>Diptera - growth & development</topic><topic>DIRECT INJURY, MYIASIS, FORENSICS</topic><topic>eosinophil</topic><topic>Eosinophilia</topic><topic>eosinophils</topic><topic>Eosinophils - immunology</topic><topic>Eosinophils - pathology</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Germinal centers</topic><topic>Hyperplasia</topic><topic>immune response</topic><topic>Leukocytes (eosinophilic)</topic><topic>Leukocytes (neutrophilic)</topic><topic>Lymph nodes</topic><topic>Lymph Nodes - immunology</topic><topic>Lymph Nodes - pathology</topic><topic>Lymphadenitis</topic><topic>Lymphadenopathy</topic><topic>lymphatic diseases</topic><topic>Lymphatic Diseases - immunology</topic><topic>Lymphatic Diseases - parasitology</topic><topic>Macrophages</topic><topic>Male</topic><topic>mast cell</topic><topic>Mast cells</topic><topic>Mast Cells - immunology</topic><topic>Mast Cells - pathology</topic><topic>Mastocytosis</topic><topic>Medically important nuisances and vectors, pests of stored products and materials: population survey and control</topic><topic>Myiasis</topic><topic>Myiasis - immunology</topic><topic>Myiasis - pathology</topic><topic>Rats</topic><topic>Rats, Wistar</topic><topic>Rattus norvegicus</topic><topic>Sinus</topic><topic>Vectors. Intermediate hosts</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cardoso, P.J.G.</creatorcontrib><creatorcontrib>Leite, V.H.R.</creatorcontrib><creatorcontrib>Leite, L.H.R.</creatorcontrib><creatorcontrib>Leite, A.C.R.</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Entomology Abstracts (Full archive)</collection><jtitle>Journal of medical entomology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cardoso, P.J.G.</au><au>Leite, V.H.R.</au><au>Leite, L.H.R.</au><au>Leite, A.C.R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lymphadenopathy and Expression of Nodal Mast Cells and Eosinophils in the Myiasis by Human Bot Fly</atitle><jtitle>Journal of medical entomology</jtitle><addtitle>J Med Entomol</addtitle><date>2009-11-01</date><risdate>2009</risdate><volume>46</volume><issue>6</issue><spage>1514</spage><epage>1518</epage><pages>1514-1518</pages><issn>0022-2585</issn><eissn>1938-2928</eissn><eissn>0022-2585</eissn><coden>JMENA6</coden><abstract>Wistar rats (Rattus norvegicus) infested with Dermatobia hominis (L. Jr., 1781) had their axillary lymph nodes removed and histopathologically processed. Follicular hyperplasia in the germinal center was noted from 2 d postinfestation (dpi), exhibiting a high number of centerblasts, mitotic and apoptotic cells, and a thin parafollicular area. The paracortex showed hyperplasia rich in dendritic cells, immunoblasts, and endothelial venules, with diapedesis seen from 4 dpi onward. Hyperplasia of the medullar sinus also was first observed at this point, as well as dilated lymphatic sinus, lymph, macrophages, neutrophils, mast cells, and eosinophils. Medullar strings were expanded and filled with immunoblasts, mitotic cells, and plasmocytes. Lymphadenitis was not observed. The expression of mast cells was similar for both myiasis-affected and control rats but increased significantly (mastocytosis) at 7 and 15 d postlarval emergence (dple). Eosinophilia was observed at 4, 10, 15, 20, and 28 dpi as well as at 2, 7, and 15 dple, particularly on the last three observations of dpi and the earliest dple. This experimental approach allowed progressive tissue reactions in the lymph nodes to be monitored during myiasis, particularly those involving mast cells and eosinophils. These reactions abated and complete repair was observed at 60 dple.</abstract><cop>Lanham, MD</cop><pub>Entomological Society of America</pub><pmid>19960706</pmid><doi>10.1603/033.046.0640</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-2585 |
| ispartof | Journal of medical entomology, 2009-11, Vol.46 (6), p.1514-1518 |
| issn | 0022-2585 1938-2928 0022-2585 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_853481915 |
| source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; BioOne Complete |
| subjects | animal models Animals Apoptosis Biological and medical sciences bot flies Dendritic cells Dermatobia hominis diapedesis Diptera - growth & development DIRECT INJURY, MYIASIS, FORENSICS eosinophil Eosinophilia eosinophils Eosinophils - immunology Eosinophils - pathology Fundamental and applied biological sciences. Psychology Germinal centers Hyperplasia immune response Leukocytes (eosinophilic) Leukocytes (neutrophilic) Lymph nodes Lymph Nodes - immunology Lymph Nodes - pathology Lymphadenitis Lymphadenopathy lymphatic diseases Lymphatic Diseases - immunology Lymphatic Diseases - parasitology Macrophages Male mast cell Mast cells Mast Cells - immunology Mast Cells - pathology Mastocytosis Medically important nuisances and vectors, pests of stored products and materials: population survey and control Myiasis Myiasis - immunology Myiasis - pathology Rats Rats, Wistar Rattus norvegicus Sinus Vectors. Intermediate hosts |
| title | Lymphadenopathy and Expression of Nodal Mast Cells and Eosinophils in the Myiasis by Human Bot Fly |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-03T12%3A45%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Lymphadenopathy%20and%20Expression%20of%20Nodal%20Mast%20Cells%20and%20Eosinophils%20in%20the%20Myiasis%20by%20Human%20Bot%20Fly&rft.jtitle=Journal%20of%20medical%20entomology&rft.au=Cardoso,%20P.J.G.&rft.date=2009-11-01&rft.volume=46&rft.issue=6&rft.spage=1514&rft.epage=1518&rft.pages=1514-1518&rft.issn=0022-2585&rft.eissn=1938-2928&rft.coden=JMENA6&rft_id=info:doi/10.1603/033.046.0640&rft_dat=%3Cgale_proqu%3EA535150775%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=733603190&rft_id=info:pmid/19960706&rft_galeid=A535150775&rfr_iscdi=true |