genetic screen in Saccharomyces cerevisiae identifies new genes that interact with mex67-5, a temperature-sensitive allele of the gene encoding the mRNA export receptor

The Mex67p protein, together with Mtr2p, functions as the mRNA export receptor in Saccharomyces cerevisiae by interacting with both mRNA and nuclear pore complexes. To identify genes that interact functionally with MEX67, we used transposon insertion to search for mutations that suppressed the tempe...

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Veröffentlicht in:	Molecular genetics and genomics : MGG 2009, Vol.281 (1), p.125-134
Hauptverfasser:	Estruch, Francisco, Peiró-Chova, Lorena, Gómez-Navarro, Natalia, Durbán, Jordi, Hodge, Christine, del Olmo, Marceŀlí, Cole, Charles N
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animal Genetics and Genomics Base Sequence Biochemistry Biomedical and Life Sciences Chromosomal Proteins, Non-Histone - genetics Chromosomal Proteins, Non-Histone - metabolism Cytoplasm DNA, Fungal - genetics Exoribonucleases - genetics Exoribonucleases - metabolism Gene Expression Genes Genes, Fungal Genomes Genomics Histone Chaperones Human Genetics Life Sciences Microbial Genetics and Genomics Models, Biological Mutagenesis, Insertional Mutation Nuclear Proteins - genetics Nuclear Proteins - metabolism Nucleocytoplasmic Transport Proteins - genetics Nucleocytoplasmic Transport Proteins - metabolism Original Paper Plant Genetics and Genomics Plasmids - genetics Proteins Quality control RNA, Fungal - metabolism RNA, Messenger - metabolism RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism Saccharomyces cerevisiae Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - growth & development Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Temperature Transcriptional Elongation Factors Ubiquitin-Protein Ligases - genetics Ubiquitin-Protein Ligases - metabolism Yeast
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