Kounis syndrome: two extraordinary cases

Kounis syndrome: two extraordinary cases

Acute myocardial infarction occurring during the course of an allergic reaction constitutes the Kounis syndrome. This syndrome is caused by inflammatory mediators released mainly from activated mast cells and the interrelated via bidirectional stimuli macrophages and T-lymphocytes. Since activated m...

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Veröffentlicht in:International journal of cardiology 2011, Vol.147 (2), p.e35-e38
Hauptverfasser: Almpanis, George, Siahos, Simos, Karogiannis, Nicholas C, Mazarakis, Andreas, Niarchos, Constantinos, Kounis, George N, Kounis, Nicholas G
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container_issue 2
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container_title International journal of cardiology
container_volume 147
creator Almpanis, George
Siahos, Simos
Karogiannis, Nicholas C
Mazarakis, Andreas
Niarchos, Constantinos
Kounis, George N
Kounis, Nicholas G
description Acute myocardial infarction occurring during the course of an allergic reaction constitutes the Kounis syndrome. This syndrome is caused by inflammatory mediators released mainly from activated mast cells and the interrelated via bidirectional stimuli macrophages and T-lymphocytes. Since activated mast cells abound at the areas of plaque erosion or rupture in patients suffering from acute myocardial infarction a common pathway between allergic and non allergic coronary events seems to exist. Two cases of this syndrome are described, the first following nicorette transdermal application and subsequent finger pricking by fish bone and the second after ciprofloxacin administration.
doi_str_mv 10.1016/j.ijcard.2009.01.031
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title Kounis syndrome: two extraordinary cases
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