Antiviral drug resistance and helicase–primase inhibitors of herpes simplex virus

Abstract A new class of chemical inhibitors has been discovered that interferes with the process of herpesvirus DNA replication. To date, the majority of useful herpesvirus antivirals are nucleoside analogues that block herpesvirus DNA replication by targeting the DNA polymerase. The new helicase–pr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Drug resistance updates 2011-02, Vol.14 (1), p.45-51
Hauptverfasser:	Field, Hugh J, Biswas, Subhajit
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiviral Agents - pharmacology DNA Helicases - antagonists & inhibitors DNA Primase - antagonists & inhibitors Drug Resistance, Viral Enzyme Inhibitors - pharmacology Hematology, Oncology and Palliative Medicine Herpes Genitalis - drug therapy Herpes Genitalis - enzymology Herpes Simplex - drug therapy Herpes Simplex - enzymology Herpesvirus 1, Human - drug effects Herpesvirus 1, Human - enzymology Herpesvirus 2, Human - drug effects Herpesvirus 2, Human - enzymology Humans Infectious Disease Viral Proteins - antagonists & inhibitors Virus Replication - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!