Dynamic translocation of ligand-complexed DNA through solid-state nanopores with optical tweezers

We investigated the threading and controlled translocation of individual lambda-DNA (λ-DNA) molecules through solid-state nanopores with piconewton force sensitivity, millisecond time resolution and picoampere ionic current sensitivity with a set-up combining quantitative 3D optical tweezers (OT) wi...

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Veröffentlicht in:	Journal of physics. Condensed matter 2010-11, Vol.22 (45), p.454121-454121
Hauptverfasser:	Sischka, Andy, Spiering, Andre, Khaksar, Maryam, Laxa, Miriam, König, Janine, Dietz, Karl-Josef, Anselmetti, Dario
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Biological and medical sciences Dna, deoxyribonucleoproteins DNA, Viral - chemistry DNA, Viral - ultrastructure Fundamental and applied biological sciences. Psychology Ligands Motion Nanostructures - chemistry Nanostructures - ultrastructure Nucleic acids Optical Tweezers Porosity Stress, Mechanical
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