Broad spectrum and potent antitumor activities of YM155, a novel small‐molecule survivin suppressant, in a wide variety of human cancer cell lines and xenograft models

Antitumor activities of YM155, a novel small‐molecule survivin suppressant, were investigated in a wide variety of human cancer cell lines and xenograft models. YM155 inhibited the growth of 119 human cancer cell lines, with the greatest activity in lines derived from non‐Hodgkin’s lymphoma, hormone...

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Veröffentlicht in:Cancer science 2011-03, Vol.102 (3), p.614-621
Hauptverfasser: Nakahara, Takahito, Kita, Aya, Yamanaka, Kentaro, Mori, Masamichi, Amino, Nobuaki, Takeuchi, Masahiro, Tominaga, Fumiko, Kinoyama, Isao, Matsuhisa, Akira, Kudou, Masafumi, Sasamata, Masao
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Sprache:eng
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