Liver and pancreatic fat content and metabolism in healthy monozygotic twins with discordant physical activity

Background & Aims Ectopic fat in muscle and liver is linked to obesity and type 2 diabetes. Recently, pancreatic lipid accumulation has also been associated with β-cell dysfunction and reduced insulin production, leading to the development of type 2 diabetes. Physical exercise training has been...

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Veröffentlicht in:	Journal of hepatology 2011-03, Vol.54 (3), p.545-552
Hauptverfasser:	Hannukainen, Jarna C, Borra, Ronald, Linderborg, Kaisa, Kallio, Heikki, Kiss, Jan, Lepomäki, Virva, Kalliokoski, Kari K, Kujala, Urho M, Kaprio, Jaakko, Heinonen, Olli J, Komu, Markku, Parkkola, Riitta, Ahotupa, Markku, Lehtimäki, Terho, Huupponen, Risto, Iozzo, Patricia, Nuutila, Pirjo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - anatomy & histology Adipose Tissue - metabolism Adult Animals Biological and medical sciences Fatty Acids - metabolism Fatty Acids, Nonesterified - metabolism Gastroenterology and Hepatology Gastroenterology. Liver. Pancreas. Abdomen Humans Insulin Resistance Lipid Metabolism Liver - anatomy & histology Liver - metabolism Magnetic Resonance Imaging Magnetic Resonance Spectroscopy Male Medical sciences Models, Animal Monozygotic twins Motor Activity Pancreas - anatomy & histology Pancreas - metabolism Physical activity Sus scrofa Swine Swine, Miniature Twins, Monozygotic - physiology Young Adult
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