The outcome of 5-ALA-mediated photodynamic treatment in melanoma cells is influenced by vitamin C and heme oxygenase-1

Photodynamic therapy (PDT) is an important clinical approach for cancer treatment. It involves the administration of a photosensitizer, followed by its activation with light and induction of cell death. The underlying mechanism is an increased production of reactive oxygen species (ROS) leading to o...

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Veröffentlicht in:BioFactors (Oxford) 2011-01, Vol.37 (1), p.17-24
Hauptverfasser: Grimm, Stefanie, Mvondo, Dagmar, Grune, Tilman, Breusing, Nicolle
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Sprache:eng
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