Prognostic significance of cytoplasmic SOX9 in invasive ductal carcinoma and metastatic breast cancer

SOX9, a high mobility group (HMG) box transcription factor, is required for development, differentiation and lineage commitment. It is known to exert its effects through nuclear translocation, such as cell cycle changes in response to retinoic acid treatment in breast cancer cells. However, it is no...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 2011-02, Vol.236 (2), p.145-155
Hauptverfasser:	Chakravarty, Geetika, Moroz, Krzysztof, Makridakis, Nick M, Lloyd, Shelby Alaine, Galvez, Sarah E, Canavello, Peter R, Lacey, Michelle R, Agrawal, Krishna, Mondal, Debasis
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Breast Neoplasms - diagnosis Breast Neoplasms - pathology Breast Neoplasms - secondary Carcinoma, Ductal, Breast - diagnosis Carcinoma, Ductal, Breast - pathology Carcinoma, Ductal, Breast - secondary Cytoplasm - enzymology Gene Expression Profiling Humans Immunohistochemistry Ki-67 Antigen - analysis Lymph Nodes - pathology Microarray Analysis Neoplasm Metastasis - diagnosis Neoplasm Metastasis - pathology Prognosis Severity of Illness Index SOX9 Transcription Factor - metabolism Survival Analysis
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