Predicted expansion of the claudin multigene family

Claudins (Cldn) are essential membrane proteins of tight junctions (TJs), which form the paracellular permselective barrier. They are produced by a multi-gene family of 24 reported members in mouse and human. Based on a comprehensive search combined with phylogenetic analyses, we identified three no...

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Veröffentlicht in:	FEBS letters 2011-02, Vol.585 (4), p.606-612
Hauptverfasser:	Mineta, Katsuhiko, Yamamoto, Yasuko, Yamazaki, Yuji, Tanaka, Hiroo, Tada, Yukiyo, Saito, Kuniaki, Tamura, Atsushi, Igarashi, Michihiro, Endo, Toshinori, Takeuchi, Kosei, Tsukita, Sachiko
Format:	Artikel
Sprache:	eng
Schlagworte:	adherens junction Amino Acid Sequence Animals Cell adhesion Cell Line Claudin Claudins - chemistry Claudins - genetics Claudins - metabolism Cldn Conserved Sequence Databases, Protein Dogs Epithelial cells Epithelial Cells - metabolism Epithelial Cells - ultrastructure Gene Expression Regulation, Developmental Gene Library Humans Mice Organ Specificity Paracellular barrier Phylogeny Protein Isoforms - chemistry Protein Isoforms - genetics Protein Isoforms - metabolism Protein Structure, Secondary PSI-BLAST Recombinant Proteins RNA, Messenger - metabolism Sequence Alignment Tight junction Tight Junctions - metabolism
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