Clinical examination and urinary oestrogen assays in newborn children with congenital dislocation of the hip
1. Twenty-one cases of congenital dislocation of the hip were found on examination of 1,881 consecutive neonates on the first day of life, giving an incidence of eleven per 1,000 live births. 2. Insignificant high-pitched "clicks" were noted in 10 per cent of newborn children. 3. Conversio...
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| Veröffentlicht in: | Journal of bone and joint surgery. British volume 1968-08, Vol.50 (3), p.546-550 |
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| container_title | Journal of bone and joint surgery. British volume |
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| creator | Thieme, W T Wynne-Davies, R |
| description | 1. Twenty-one cases of congenital dislocation of the hip were found on examination of 1,881 consecutive neonates on the first day of life, giving an incidence of eleven per 1,000 live births.
2. Insignificant high-pitched "clicks" were noted in 10 per cent of newborn children.
3. Conversion of half of the patients with hip dislocation to normal occurred during the first post-natal week.
4. Joint laxity was not a feature of the newborn with congenital dislocation of the hip.
5. Oestradiol, oestrone and oestriol were estimated in twenty-fourhour urine samples collected from sixteen patients with congenital dislocation of the hip and nineteen matched controls during the first six days of life. No significant differences in oestrogen output between the two groups were found.
6. The hypothesis that congenital dislocation of the hip is a result of an inborn error of oestrogen metabolism in the newborn is not supported. |
| doi_str_mv | 10.1302/0301-620x.50b3.546 |
| format | Article |
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2. Insignificant high-pitched "clicks" were noted in 10 per cent of newborn children.
3. Conversion of half of the patients with hip dislocation to normal occurred during the first post-natal week.
4. Joint laxity was not a feature of the newborn with congenital dislocation of the hip.
5. Oestradiol, oestrone and oestriol were estimated in twenty-fourhour urine samples collected from sixteen patients with congenital dislocation of the hip and nineteen matched controls during the first six days of life. No significant differences in oestrogen output between the two groups were found.
6. The hypothesis that congenital dislocation of the hip is a result of an inborn error of oestrogen metabolism in the newborn is not supported.</description><identifier>ISSN: 0301-620X</identifier><identifier>EISSN: 2044-5377</identifier><identifier>DOI: 10.1302/0301-620x.50b3.546</identifier><identifier>PMID: 5726907</identifier><language>eng</language><publisher>England</publisher><subject>Estradiol - urine ; Estriol - urine ; Estrogens - metabolism ; Estrone - urine ; Female ; Hip Dislocation, Congenital - diagnosis ; Hip Dislocation, Congenital - epidemiology ; Hip Dislocation, Congenital - etiology ; Hip Dislocation, Congenital - urine ; Humans ; Infant, Newborn ; Male ; Metabolism, Inborn Errors - complications ; Scotland</subject><ispartof>Journal of bone and joint surgery. British volume, 1968-08, Vol.50 (3), p.546-550</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c213t-68e42a8e9b220681e6c76a4637591fa8132b795a9a19079355700f23d187ab9d3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5726907$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Thieme, W T</creatorcontrib><creatorcontrib>Wynne-Davies, R</creatorcontrib><title>Clinical examination and urinary oestrogen assays in newborn children with congenital dislocation of the hip</title><title>Journal of bone and joint surgery. British volume</title><addtitle>J Bone Joint Surg Br</addtitle><description>1. Twenty-one cases of congenital dislocation of the hip were found on examination of 1,881 consecutive neonates on the first day of life, giving an incidence of eleven per 1,000 live births.
2. Insignificant high-pitched "clicks" were noted in 10 per cent of newborn children.
3. Conversion of half of the patients with hip dislocation to normal occurred during the first post-natal week.
4. Joint laxity was not a feature of the newborn with congenital dislocation of the hip.
5. Oestradiol, oestrone and oestriol were estimated in twenty-fourhour urine samples collected from sixteen patients with congenital dislocation of the hip and nineteen matched controls during the first six days of life. No significant differences in oestrogen output between the two groups were found.
6. The hypothesis that congenital dislocation of the hip is a result of an inborn error of oestrogen metabolism in the newborn is not supported.</description><subject>Estradiol - urine</subject><subject>Estriol - urine</subject><subject>Estrogens - metabolism</subject><subject>Estrone - urine</subject><subject>Female</subject><subject>Hip Dislocation, Congenital - diagnosis</subject><subject>Hip Dislocation, Congenital - epidemiology</subject><subject>Hip Dislocation, Congenital - etiology</subject><subject>Hip Dislocation, Congenital - urine</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Metabolism, Inborn Errors - complications</subject><subject>Scotland</subject><issn>0301-620X</issn><issn>2044-5377</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1968</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kE9LAzEQxYMotVa_gCDk5G3rJNkku0ct_oOCFwVvIbubdSPbpCa7tP32prR6GmbmzWPeD6FrAnPCgN4BA5IJCts5h4rNeS5O0JRCnmecSXmKpn-Cz3N0EeM3AOScswmacElFCXKK-kVvna11j81Wr6zTg_UOa9fgMaQu7LA3cQj-y6RpjHoXsXXYmU3lg8N1Z_smpNXGDh2uvUsyOySzxsbe1wcz3-KhM7iz60t01uo-mqtjnaGPp8f3xUu2fHt-Xdwvs5oSNmSiMDnVhSkrSkEUxIhaCp0LJnlJWl0QRitZcl1qkjKUjHMJ0FLWkELqqmzYDN0efNfB_4zpf7WysTZ9r53xY1QFByHznCchPQjr4GMMplXrYFcptSKg9ojVnqDaE1QcHphKiNPRzdF9rFam-T85MmW_nD536w</recordid><startdate>196808</startdate><enddate>196808</enddate><creator>Thieme, W T</creator><creator>Wynne-Davies, R</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196808</creationdate><title>Clinical examination and urinary oestrogen assays in newborn children with congenital dislocation of the hip</title><author>Thieme, W T ; Wynne-Davies, R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c213t-68e42a8e9b220681e6c76a4637591fa8132b795a9a19079355700f23d187ab9d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1968</creationdate><topic>Estradiol - urine</topic><topic>Estriol - urine</topic><topic>Estrogens - metabolism</topic><topic>Estrone - urine</topic><topic>Female</topic><topic>Hip Dislocation, Congenital - diagnosis</topic><topic>Hip Dislocation, Congenital - epidemiology</topic><topic>Hip Dislocation, Congenital - etiology</topic><topic>Hip Dislocation, Congenital - urine</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Metabolism, Inborn Errors - complications</topic><topic>Scotland</topic><toplevel>online_resources</toplevel><creatorcontrib>Thieme, W T</creatorcontrib><creatorcontrib>Wynne-Davies, R</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of bone and joint surgery. British volume</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thieme, W T</au><au>Wynne-Davies, R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical examination and urinary oestrogen assays in newborn children with congenital dislocation of the hip</atitle><jtitle>Journal of bone and joint surgery. British volume</jtitle><addtitle>J Bone Joint Surg Br</addtitle><date>1968-08</date><risdate>1968</risdate><volume>50</volume><issue>3</issue><spage>546</spage><epage>550</epage><pages>546-550</pages><issn>0301-620X</issn><eissn>2044-5377</eissn><abstract>1. Twenty-one cases of congenital dislocation of the hip were found on examination of 1,881 consecutive neonates on the first day of life, giving an incidence of eleven per 1,000 live births.
2. Insignificant high-pitched "clicks" were noted in 10 per cent of newborn children.
3. Conversion of half of the patients with hip dislocation to normal occurred during the first post-natal week.
4. Joint laxity was not a feature of the newborn with congenital dislocation of the hip.
5. Oestradiol, oestrone and oestriol were estimated in twenty-fourhour urine samples collected from sixteen patients with congenital dislocation of the hip and nineteen matched controls during the first six days of life. No significant differences in oestrogen output between the two groups were found.
6. The hypothesis that congenital dislocation of the hip is a result of an inborn error of oestrogen metabolism in the newborn is not supported.</abstract><cop>England</cop><pmid>5726907</pmid><doi>10.1302/0301-620x.50b3.546</doi><tpages>5</tpages></addata></record> |
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| identifier | ISSN: 0301-620X |
| ispartof | Journal of bone and joint surgery. British volume, 1968-08, Vol.50 (3), p.546-550 |
| issn | 0301-620X 2044-5377 |
| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Estradiol - urine Estriol - urine Estrogens - metabolism Estrone - urine Female Hip Dislocation, Congenital - diagnosis Hip Dislocation, Congenital - epidemiology Hip Dislocation, Congenital - etiology Hip Dislocation, Congenital - urine Humans Infant, Newborn Male Metabolism, Inborn Errors - complications Scotland |
| title | Clinical examination and urinary oestrogen assays in newborn children with congenital dislocation of the hip |
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