Evaluation of the Health Utilities Index Mark-3 in Heart Failure
Abstract Background The purpose of this study was to evaluate the reliability, validity, and responsiveness to change of the Health Utilities Index Mark-3 (HUI-3) in heart failure (HF) for use in cost-effectiveness studies. Methods and Results Two hundred eleven patients with HF recruited from outpa...
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| Veröffentlicht in: | Journal of cardiac failure 2011-02, Vol.17 (2), p.143-150 |
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| creator | Pressler, Susan J., RN, PhD Eckert, George J., MAS Morrison, Gwendolyn C., PhD Murray, Michael D., PharmD, MPH Oldridge, Neil B., PhD |
| description | Abstract Background The purpose of this study was to evaluate the reliability, validity, and responsiveness to change of the Health Utilities Index Mark-3 (HUI-3) in heart failure (HF) for use in cost-effectiveness studies. Methods and Results Two hundred eleven patients with HF recruited from outpatient clinics were enrolled; 165 completed the 26-week study. Patients completed 4 health-related quality of life questionnaires (baseline and 4, 8, and 26 weeks), including the HUI-3, the Medical Outcomes Study Short-form 12 (SF-12), the Minnesota Living with Heart Failure Questionnaire (LHFQ), and the Chronic Heart Failure Questionnaire (CHQ). The HUI-3 indicated moderate or fair health-related quality of life overall; the attributes most impaired were pain, ambulation, cognition, and emotion. Internal consistency reliability (Cronbach’s alpha = 0.51) was low and test-retest reliability (intraclass correlation coefficient = 0.68) was adequate. The HUI-3 total score was significantly associated with the SF-12, LHFQ, and CHQ total scores. It discriminated among patients with varying New York Heart Association class ( P < .001) and varying perceived health ( P < .001). The HUI-3 was less responsive to perceived change in health condition than the LHFQ or the CHQ. Conclusions The HUI-3 demonstrated satisfactory reliability and validity in this sample supporting its use in cost-effectiveness studies. |
| doi_str_mv | 10.1016/j.cardfail.2010.08.014 |
| format | Article |
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Methods and Results Two hundred eleven patients with HF recruited from outpatient clinics were enrolled; 165 completed the 26-week study. Patients completed 4 health-related quality of life questionnaires (baseline and 4, 8, and 26 weeks), including the HUI-3, the Medical Outcomes Study Short-form 12 (SF-12), the Minnesota Living with Heart Failure Questionnaire (LHFQ), and the Chronic Heart Failure Questionnaire (CHQ). The HUI-3 indicated moderate or fair health-related quality of life overall; the attributes most impaired were pain, ambulation, cognition, and emotion. Internal consistency reliability (Cronbach’s alpha = 0.51) was low and test-retest reliability (intraclass correlation coefficient = 0.68) was adequate. The HUI-3 total score was significantly associated with the SF-12, LHFQ, and CHQ total scores. It discriminated among patients with varying New York Heart Association class ( P < .001) and varying perceived health ( P < .001). The HUI-3 was less responsive to perceived change in health condition than the LHFQ or the CHQ. Conclusions The HUI-3 demonstrated satisfactory reliability and validity in this sample supporting its use in cost-effectiveness studies.</description><identifier>ISSN: 1071-9164</identifier><identifier>EISSN: 1532-8414</identifier><identifier>DOI: 10.1016/j.cardfail.2010.08.014</identifier><identifier>PMID: 21300304</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Cardiovascular ; Cost-Benefit Analysis ; Female ; Health Status Indicators ; health utilities ; Health-related quality of life ; heart failure ; Heart Failure - diagnosis ; Heart Failure - pathology ; Heart Failure - psychology ; HUI-3 ; Humans ; Male ; Middle Aged ; Psychometrics ; quality of life ; Quality of Life - psychology ; Reproducibility of Results ; Statistics, Nonparametric ; Surveys and Questionnaires ; Young Adult</subject><ispartof>Journal of cardiac failure, 2011-02, Vol.17 (2), p.143-150</ispartof><rights>Elsevier Inc.</rights><rights>2011 Elsevier Inc.</rights><rights>Copyright © 2011 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c422t-cbc66e3ef055a11fb061fac138aad0ae23dd053d847dccfe4bef58d02d7d34023</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.cardfail.2010.08.014$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,45974</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21300304$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pressler, Susan J., RN, PhD</creatorcontrib><creatorcontrib>Eckert, George J., MAS</creatorcontrib><creatorcontrib>Morrison, Gwendolyn C., PhD</creatorcontrib><creatorcontrib>Murray, Michael D., PharmD, MPH</creatorcontrib><creatorcontrib>Oldridge, Neil B., PhD</creatorcontrib><title>Evaluation of the Health Utilities Index Mark-3 in Heart Failure</title><title>Journal of cardiac failure</title><addtitle>J Card Fail</addtitle><description>Abstract Background The purpose of this study was to evaluate the reliability, validity, and responsiveness to change of the Health Utilities Index Mark-3 (HUI-3) in heart failure (HF) for use in cost-effectiveness studies. Methods and Results Two hundred eleven patients with HF recruited from outpatient clinics were enrolled; 165 completed the 26-week study. Patients completed 4 health-related quality of life questionnaires (baseline and 4, 8, and 26 weeks), including the HUI-3, the Medical Outcomes Study Short-form 12 (SF-12), the Minnesota Living with Heart Failure Questionnaire (LHFQ), and the Chronic Heart Failure Questionnaire (CHQ). The HUI-3 indicated moderate or fair health-related quality of life overall; the attributes most impaired were pain, ambulation, cognition, and emotion. Internal consistency reliability (Cronbach’s alpha = 0.51) was low and test-retest reliability (intraclass correlation coefficient = 0.68) was adequate. The HUI-3 total score was significantly associated with the SF-12, LHFQ, and CHQ total scores. It discriminated among patients with varying New York Heart Association class ( P < .001) and varying perceived health ( P < .001). The HUI-3 was less responsive to perceived change in health condition than the LHFQ or the CHQ. Conclusions The HUI-3 demonstrated satisfactory reliability and validity in this sample supporting its use in cost-effectiveness studies.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Cardiovascular</subject><subject>Cost-Benefit Analysis</subject><subject>Female</subject><subject>Health Status Indicators</subject><subject>health utilities</subject><subject>Health-related quality of life</subject><subject>heart failure</subject><subject>Heart Failure - diagnosis</subject><subject>Heart Failure - pathology</subject><subject>Heart Failure - psychology</subject><subject>HUI-3</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Psychometrics</subject><subject>quality of life</subject><subject>Quality of Life - psychology</subject><subject>Reproducibility of Results</subject><subject>Statistics, Nonparametric</subject><subject>Surveys and Questionnaires</subject><subject>Young Adult</subject><issn>1071-9164</issn><issn>1532-8414</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkctOBCEQRYnR-P4F0ztXPRaP7mE2RmPGR6Jxoa4JA0VkZLoVaKN_L51RF25cQcipe8MpQo4oTCjQ9mQ5MTpap32YMCiPICdAxQbZpQ1ntRRUbJY7TGk9o63YIXspLQFACphukx1GOQAHsUvO5u86DDr7vqt6V-VnrK5Rh_xcPWUffPaYqpvO4kd1p-NLzSvfjUDM1WXpHiIekC2nQ8LD73OfPF3OHy-u69v7q5uL89vaCMZybRambZGjg6bRlLoFtNRpQ7nU2oJGxq2FhlspptYYh2KBrpEWmJ1aLoDxfXK8zn2N_duAKauVTwZD0B32Q1KygaYVcjaS7Zo0sU8polOv0a90_FQU1ChPLdWPPDXKUyBVkVcGj74rhsUK7e_Yj60CnK0BLB999xhVMh47g9ZHNFnZ3v_fcfonwgTfeaPDC35iWvZD7IpGRVViCtTDuMJxgxRKyExI_gXefZeU</recordid><startdate>20110201</startdate><enddate>20110201</enddate><creator>Pressler, Susan J., RN, PhD</creator><creator>Eckert, George J., MAS</creator><creator>Morrison, Gwendolyn C., PhD</creator><creator>Murray, Michael D., PharmD, MPH</creator><creator>Oldridge, Neil B., PhD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20110201</creationdate><title>Evaluation of the Health Utilities Index Mark-3 in Heart Failure</title><author>Pressler, Susan J., RN, PhD ; Eckert, George J., MAS ; Morrison, Gwendolyn C., PhD ; Murray, Michael D., PharmD, MPH ; Oldridge, Neil B., PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c422t-cbc66e3ef055a11fb061fac138aad0ae23dd053d847dccfe4bef58d02d7d34023</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Cardiovascular</topic><topic>Cost-Benefit Analysis</topic><topic>Female</topic><topic>Health Status Indicators</topic><topic>health utilities</topic><topic>Health-related quality of life</topic><topic>heart failure</topic><topic>Heart Failure - diagnosis</topic><topic>Heart Failure - pathology</topic><topic>Heart Failure - psychology</topic><topic>HUI-3</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Psychometrics</topic><topic>quality of life</topic><topic>Quality of Life - psychology</topic><topic>Reproducibility of Results</topic><topic>Statistics, Nonparametric</topic><topic>Surveys and Questionnaires</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pressler, Susan J., RN, PhD</creatorcontrib><creatorcontrib>Eckert, George J., MAS</creatorcontrib><creatorcontrib>Morrison, Gwendolyn C., PhD</creatorcontrib><creatorcontrib>Murray, Michael D., PharmD, MPH</creatorcontrib><creatorcontrib>Oldridge, Neil B., PhD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cardiac failure</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pressler, Susan J., RN, PhD</au><au>Eckert, George J., MAS</au><au>Morrison, Gwendolyn C., PhD</au><au>Murray, Michael D., PharmD, MPH</au><au>Oldridge, Neil B., PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of the Health Utilities Index Mark-3 in Heart Failure</atitle><jtitle>Journal of cardiac failure</jtitle><addtitle>J Card Fail</addtitle><date>2011-02-01</date><risdate>2011</risdate><volume>17</volume><issue>2</issue><spage>143</spage><epage>150</epage><pages>143-150</pages><issn>1071-9164</issn><eissn>1532-8414</eissn><abstract>Abstract Background The purpose of this study was to evaluate the reliability, validity, and responsiveness to change of the Health Utilities Index Mark-3 (HUI-3) in heart failure (HF) for use in cost-effectiveness studies. Methods and Results Two hundred eleven patients with HF recruited from outpatient clinics were enrolled; 165 completed the 26-week study. Patients completed 4 health-related quality of life questionnaires (baseline and 4, 8, and 26 weeks), including the HUI-3, the Medical Outcomes Study Short-form 12 (SF-12), the Minnesota Living with Heart Failure Questionnaire (LHFQ), and the Chronic Heart Failure Questionnaire (CHQ). The HUI-3 indicated moderate or fair health-related quality of life overall; the attributes most impaired were pain, ambulation, cognition, and emotion. Internal consistency reliability (Cronbach’s alpha = 0.51) was low and test-retest reliability (intraclass correlation coefficient = 0.68) was adequate. The HUI-3 total score was significantly associated with the SF-12, LHFQ, and CHQ total scores. It discriminated among patients with varying New York Heart Association class ( P < .001) and varying perceived health ( P < .001). The HUI-3 was less responsive to perceived change in health condition than the LHFQ or the CHQ. Conclusions The HUI-3 demonstrated satisfactory reliability and validity in this sample supporting its use in cost-effectiveness studies.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>21300304</pmid><doi>10.1016/j.cardfail.2010.08.014</doi><tpages>8</tpages></addata></record> |
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| subjects | Adult Aged Aged, 80 and over Cardiovascular Cost-Benefit Analysis Female Health Status Indicators health utilities Health-related quality of life heart failure Heart Failure - diagnosis Heart Failure - pathology Heart Failure - psychology HUI-3 Humans Male Middle Aged Psychometrics quality of life Quality of Life - psychology Reproducibility of Results Statistics, Nonparametric Surveys and Questionnaires Young Adult |
| title | Evaluation of the Health Utilities Index Mark-3 in Heart Failure |
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