2-Phenylsubstituted-3-Hydroxyquinolin-4(1H)-one-Carboxamides: Structure-Cytotoxic Activity Relationship Study

A structure−activity relationship of some derivatives of 2-phenylsubstituted- 3-hydroxyquinolin-4(1H)-one-7-carboxamides was systematically studied using combinatorial solid-phase synthesis and in vitro cytotoxic activity screening on representative cancer lines. The effect of substituent type in po...

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Veröffentlicht in:ACS combinatorial science 2011-01, Vol.13 (1), p.39-44
Hauptverfasser: Soural, Miroslav, Hlaváč, Jan, Funk, Petr, Džubák, Petr, Hajdúch, Marián
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Sprache:eng
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