BLOOD LEVELS OF MEPIVACAINE AFTER REGIONAL ANAESTHESIA

BLOOD LEVELS OF MEPIVACAINE AFTER REGIONAL ANAESTHESIA

Blood levels of mepivacaine as a function of time have been recorded in two types of regional anaesthesia, namely brachial plexus blocks and infiltrations for inguinal hernia repair. In brachial plexus blocks it has been shown that the addition of adrenaline (5 μg/ml) does not alter the maximal bloo...

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Veröffentlicht in:British journal of anaesthesia : BJA 1965-10, Vol.37 (10), p.746-752
Hauptverfasser: DHUNÉR, K-G., HARTHON, J.G.L., HERBRING, B-G., LIE, T.
Format: Artikel
Sprache:eng
Schlagworte:
Anesthesia, Conduction
Autonomic Nerve Block
Blood Chemical Analysis
Brachial Plexus
Epinephrine - pharmacology
Hernia, Inguinal - surgery
Humans
Mepivacaine - metabolism
Spectrophotometry
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Zusammenfassung:Blood levels of mepivacaine as a function of time have been recorded in two types of regional anaesthesia, namely brachial plexus blocks and infiltrations for inguinal hernia repair. In brachial plexus blocks it has been shown that the addition of adrenaline (5 μg/ml) does not alter the maximal blood concentration of mepivacaine. With in filtrations for repair of inguinal hernia, however, the addition of adrenaline resulted in lower blood concentrations and a delay in the time of maximum concentration.
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/37.10.746