Immunologic screening test for carcinoma of the pancreas
Extracts of normal, inflamed, and malignant pancreas were tested by electroimmune diffusion against a randomly selected panel of normal sera and of sera from patients with pancreatitis, carcinoma of the pancreas, diabetes, other related malignant disorders, and autoimmune disorders. Seven of eight p...
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Veröffentlicht in: | The American journal of surgery 1968-11, Vol.116 (5), p.700-703 |
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container_title | The American journal of surgery |
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creator | Weiland, Dennis E. Kuntz, Daniel J. Childers, David |
description | Extracts of normal, inflamed, and malignant pancreas were tested by electroimmune diffusion against a randomly selected panel of normal sera and of sera from patients with pancreatitis, carcinoma of the pancreas, diabetes, other related malignant disorders, and autoimmune disorders. Seven of eight patients with carcinoma of the pancreas showed positive reactions. Other positive reactions were noted in sera of some patients with pancreatitis and with unrelated malignant lesions; these reactions were completely absorbed by absorbing the sera with extracts of normal or inflamed pancreas. Absorption of the sera from patients with carcinoma of the pancreas with these extracts still left a component that reacted only with malignant extracts.
A simple screening test for carcinoma of the pancreas is proposed. |
doi_str_mv | 10.1016/0002-9610(68)90351-6 |
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A simple screening test for carcinoma of the pancreas is proposed.</description><subject>Autoantibodies - analysis</subject><subject>Blood Protein Electrophoresis</subject><subject>Humans</subject><subject>Isoantibodies - analysis</subject><subject>Pancreatic Neoplasms - diagnosis</subject><subject>Pancreatic Neoplasms - immunology</subject><subject>Precipitin Tests</subject><subject>Tissue Extracts</subject><issn>0002-9610</issn><issn>1879-1883</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1968</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE9PwzAMxSMEGmPwDUDqCcGhEDdpml6Qpok_kyZxgXOUpO4IapuRtEh8ezo27cjJsvzes_0j5BLoHVAQ95TSLC0F0Bshb0vKckjFEZmCLMoUpGTHZHqQnJKzGD_HFoCzCZnkQuYS5JTIZdsOnW_82tkk2oDYuW6d9Bj7pPYhsTpY1_lWJ75O-g9MNrobVTqek5NaNxEv9nVG3p8e3xYv6er1ebmYr1KbFVmfQgmVAV3rorLAa9SWCcwM04ZLFJkBipAXpoKyFJzyoubIsJQGpKaiypDNyPUudxP81zCepVoXLTaN7tAPUcmcUsEyOgr5TmiDjzFgrTbBtTr8KKBqC0xtaagtDSWk-gOmxGi72ucPpsXqYNoTGucPuzmOT347DCpah53FygW0vaq8-3_BL5--eZs</recordid><startdate>196811</startdate><enddate>196811</enddate><creator>Weiland, Dennis E.</creator><creator>Kuntz, Daniel J.</creator><creator>Childers, David</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196811</creationdate><title>Immunologic screening test for carcinoma of the pancreas</title><author>Weiland, Dennis E. ; Kuntz, Daniel J. ; Childers, David</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c272t-191db1afa7dc14feac36e2b3ab48e62b10e157bd19964047f4e3e98b18a06d2e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1968</creationdate><topic>Autoantibodies - analysis</topic><topic>Blood Protein Electrophoresis</topic><topic>Humans</topic><topic>Isoantibodies - analysis</topic><topic>Pancreatic Neoplasms - diagnosis</topic><topic>Pancreatic Neoplasms - immunology</topic><topic>Precipitin Tests</topic><topic>Tissue Extracts</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Weiland, Dennis E.</creatorcontrib><creatorcontrib>Kuntz, Daniel J.</creatorcontrib><creatorcontrib>Childers, David</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Weiland, Dennis E.</au><au>Kuntz, Daniel J.</au><au>Childers, David</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Immunologic screening test for carcinoma of the pancreas</atitle><jtitle>The American journal of surgery</jtitle><addtitle>Am J Surg</addtitle><date>1968-11</date><risdate>1968</risdate><volume>116</volume><issue>5</issue><spage>700</spage><epage>703</epage><pages>700-703</pages><issn>0002-9610</issn><eissn>1879-1883</eissn><abstract>Extracts of normal, inflamed, and malignant pancreas were tested by electroimmune diffusion against a randomly selected panel of normal sera and of sera from patients with pancreatitis, carcinoma of the pancreas, diabetes, other related malignant disorders, and autoimmune disorders. Seven of eight patients with carcinoma of the pancreas showed positive reactions. Other positive reactions were noted in sera of some patients with pancreatitis and with unrelated malignant lesions; these reactions were completely absorbed by absorbing the sera with extracts of normal or inflamed pancreas. Absorption of the sera from patients with carcinoma of the pancreas with these extracts still left a component that reacted only with malignant extracts.
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source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
subjects | Autoantibodies - analysis Blood Protein Electrophoresis Humans Isoantibodies - analysis Pancreatic Neoplasms - diagnosis Pancreatic Neoplasms - immunology Precipitin Tests Tissue Extracts |
title | Immunologic screening test for carcinoma of the pancreas |
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