Cellular uptake of 3H-actinomycin D in the hematological tissues and liver of the mouse

Actinomycin D(AM), an inhibitor of DNA‐dependent RNA synthesis, produces a reversible cessation of red blood cell production. This study examines the in vivo cellular uptake of 3H‐AM in the hematological tissues and livers of B6D2F1 mice. 3H‐Am (sp. act. = 2.97 to 4.20 C/mmole) was given IV at a dos...

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Veröffentlicht in:	Journal of cellular physiology 1968-10, Vol.72 (2), p.89-95
1. Verfasser:	Cohen, Natalie S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoradiography Blood Cells - metabolism Bone Marrow - metabolism Dactinomycin - metabolism Eosinophils - metabolism Erythrocytes - metabolism Liver - metabolism Lymphocytes - metabolism Lymphoid Tissue - metabolism Mice Monocytes - metabolism Mononuclear Phagocyte System - metabolism Neutrophils - metabolism Spleen - metabolism Tritium
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