Calcium and secretion in normal and supersensitive submaxillary glands of the cat

The effect of stimulation of normal and supersensitive cat salivary glands on the subcellular distribution of hexosamine, calcium and protein has been examined. Selective accumulation of calcium and hexosamine in the granular mucin fraction especially of stimulated glands accompanying a greater secr...

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Veröffentlicht in:Biochemical pharmacology 1968-09, Vol.17 (9), p.1881-1892
Hauptverfasser: Burford, Hugh J., Gill, James B.
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container_end_page 1892
container_issue 9
container_start_page 1881
container_title Biochemical pharmacology
container_volume 17
creator Burford, Hugh J.
Gill, James B.
description The effect of stimulation of normal and supersensitive cat salivary glands on the subcellular distribution of hexosamine, calcium and protein has been examined. Selective accumulation of calcium and hexosamine in the granular mucin fraction especially of stimulated glands accompanying a greater secretion of hexosamine and calcium indicates that stimulation leads to accelerated hexosamine synthesis with a concomitant increased uptake of calcium into the gland. The possible meaning of the relative amounts of granular hexosamine, calcium and protein are discussed in relation to the formation of hexosamine-rich granules after the secretory stimulus.
doi_str_mv 10.1016/0006-2952(68)90104-4
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ispartof Biochemical pharmacology, 1968-09, Vol.17 (9), p.1881-1892
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1873-2968
language eng
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Animals
Calcium - blood
Calcium - metabolism
Calcium Isotopes
Cats
Female
Hexosamines - metabolism
Male
Proteins - metabolism
Saliva - analysis
Salivation
Secretory Rate
Submandibular Gland - enzymology
Submandibular Gland - metabolism
title Calcium and secretion in normal and supersensitive submaxillary glands of the cat
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