Calcium and secretion in normal and supersensitive submaxillary glands of the cat
The effect of stimulation of normal and supersensitive cat salivary glands on the subcellular distribution of hexosamine, calcium and protein has been examined. Selective accumulation of calcium and hexosamine in the granular mucin fraction especially of stimulated glands accompanying a greater secr...
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Veröffentlicht in: | Biochemical pharmacology 1968-09, Vol.17 (9), p.1881-1892 |
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container_end_page | 1892 |
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container_issue | 9 |
container_start_page | 1881 |
container_title | Biochemical pharmacology |
container_volume | 17 |
creator | Burford, Hugh J. Gill, James B. |
description | The effect of stimulation of normal and supersensitive cat salivary glands on the subcellular distribution of hexosamine, calcium and protein has been examined. Selective accumulation of calcium and hexosamine in the granular mucin fraction especially of stimulated glands accompanying a greater secretion of hexosamine and calcium indicates that stimulation leads to accelerated hexosamine synthesis with a concomitant increased uptake of calcium into the gland. The possible meaning of the relative amounts of granular hexosamine, calcium and protein are discussed in relation to the formation of hexosamine-rich granules after the secretory stimulus. |
doi_str_mv | 10.1016/0006-2952(68)90104-4 |
format | Article |
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Selective accumulation of calcium and hexosamine in the granular mucin fraction especially of stimulated glands accompanying a greater secretion of hexosamine and calcium indicates that stimulation leads to accelerated hexosamine synthesis with a concomitant increased uptake of calcium into the gland. The possible meaning of the relative amounts of granular hexosamine, calcium and protein are discussed in relation to the formation of hexosamine-rich granules after the secretory stimulus.</description><identifier>ISSN: 0006-2952</identifier><identifier>EISSN: 1873-2968</identifier><identifier>DOI: 10.1016/0006-2952(68)90104-4</identifier><identifier>PMID: 5688275</identifier><language>eng</language><publisher>England: Elsevier Inc</publisher><subject>Animals ; Calcium - blood ; Calcium - metabolism ; Calcium Isotopes ; Cats ; Female ; Hexosamines - metabolism ; Male ; Proteins - metabolism ; Saliva - analysis ; Salivation ; Secretory Rate ; Submandibular Gland - enzymology ; Submandibular Gland - metabolism</subject><ispartof>Biochemical pharmacology, 1968-09, Vol.17 (9), p.1881-1892</ispartof><rights>1968</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-4685f339433795d71f08c39a46834da837f6b05b9d99403157b2c74a75c79e533</citedby><cites>FETCH-LOGICAL-c357t-4685f339433795d71f08c39a46834da837f6b05b9d99403157b2c74a75c79e533</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/0006295268901044$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5688275$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Burford, Hugh J.</creatorcontrib><creatorcontrib>Gill, James B.</creatorcontrib><title>Calcium and secretion in normal and supersensitive submaxillary glands of the cat</title><title>Biochemical pharmacology</title><addtitle>Biochem Pharmacol</addtitle><description>The effect of stimulation of normal and supersensitive cat salivary glands on the subcellular distribution of hexosamine, calcium and protein has been examined. Selective accumulation of calcium and hexosamine in the granular mucin fraction especially of stimulated glands accompanying a greater secretion of hexosamine and calcium indicates that stimulation leads to accelerated hexosamine synthesis with a concomitant increased uptake of calcium into the gland. The possible meaning of the relative amounts of granular hexosamine, calcium and protein are discussed in relation to the formation of hexosamine-rich granules after the secretory stimulus.</description><subject>Animals</subject><subject>Calcium - blood</subject><subject>Calcium - metabolism</subject><subject>Calcium Isotopes</subject><subject>Cats</subject><subject>Female</subject><subject>Hexosamines - metabolism</subject><subject>Male</subject><subject>Proteins - metabolism</subject><subject>Saliva - analysis</subject><subject>Salivation</subject><subject>Secretory Rate</subject><subject>Submandibular Gland - enzymology</subject><subject>Submandibular Gland - metabolism</subject><issn>0006-2952</issn><issn>1873-2968</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1968</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtKAzEUhoMotVbfQGFWoovRZHLfCFK8QUEEXYdM5oxG5lKTadG3N3VKl64O5z__uX0InRJ8RTAR1xhjkReaFxdCXWpMMMvZHpoSJWmShdpH053lEB3F-LlJlSATNOFCqULyKXqZ28b5VZvZrsoiuACD77vMd1nXh9Y2o75aQojQRT_4NaS0bO23bxobfrL3Jjli1tfZ8AGZs8MxOqhtE-FkG2fo7f7udf6YL54fnua3i9xRLoecCcVrSjWjVGpeSVJj5ai2SaessorKWpSYl7rSmmFKuCwLJ5mV3EkNnNIZOh_nLkP_tYI4mNZHB-mqDvpVNIppTQgvkpGNRhf6GAPUZhl8m243BJsNSbPhYjaYjFDmj6Rhqe1sOz-9C9WuaYsu1W_GOqQn1x6Cic5D56DyAdxgqt7_v-AX8UiBZA</recordid><startdate>196809</startdate><enddate>196809</enddate><creator>Burford, Hugh J.</creator><creator>Gill, James B.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196809</creationdate><title>Calcium and secretion in normal and supersensitive submaxillary glands of the cat</title><author>Burford, Hugh J. ; Gill, James B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-4685f339433795d71f08c39a46834da837f6b05b9d99403157b2c74a75c79e533</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1968</creationdate><topic>Animals</topic><topic>Calcium - blood</topic><topic>Calcium - metabolism</topic><topic>Calcium Isotopes</topic><topic>Cats</topic><topic>Female</topic><topic>Hexosamines - metabolism</topic><topic>Male</topic><topic>Proteins - metabolism</topic><topic>Saliva - analysis</topic><topic>Salivation</topic><topic>Secretory Rate</topic><topic>Submandibular Gland - enzymology</topic><topic>Submandibular Gland - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Burford, Hugh J.</creatorcontrib><creatorcontrib>Gill, James B.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Biochemical pharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Burford, Hugh J.</au><au>Gill, James B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Calcium and secretion in normal and supersensitive submaxillary glands of the cat</atitle><jtitle>Biochemical pharmacology</jtitle><addtitle>Biochem Pharmacol</addtitle><date>1968-09</date><risdate>1968</risdate><volume>17</volume><issue>9</issue><spage>1881</spage><epage>1892</epage><pages>1881-1892</pages><issn>0006-2952</issn><eissn>1873-2968</eissn><abstract>The effect of stimulation of normal and supersensitive cat salivary glands on the subcellular distribution of hexosamine, calcium and protein has been examined. Selective accumulation of calcium and hexosamine in the granular mucin fraction especially of stimulated glands accompanying a greater secretion of hexosamine and calcium indicates that stimulation leads to accelerated hexosamine synthesis with a concomitant increased uptake of calcium into the gland. The possible meaning of the relative amounts of granular hexosamine, calcium and protein are discussed in relation to the formation of hexosamine-rich granules after the secretory stimulus.</abstract><cop>England</cop><pub>Elsevier Inc</pub><pmid>5688275</pmid><doi>10.1016/0006-2952(68)90104-4</doi><tpages>12</tpages></addata></record> |
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language | eng |
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source | MEDLINE; Elsevier ScienceDirect Journals |
subjects | Animals Calcium - blood Calcium - metabolism Calcium Isotopes Cats Female Hexosamines - metabolism Male Proteins - metabolism Saliva - analysis Salivation Secretory Rate Submandibular Gland - enzymology Submandibular Gland - metabolism |
title | Calcium and secretion in normal and supersensitive submaxillary glands of the cat |
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