Consensus statement on diagnosis and clinical management of Klinefelter syndrome
Nearly 70 years after its description, Klinefelter syndrome (KS) remains a largely undiagnosed condition. As its clinical presentation may be subtle, many of those affected may be unaware or diagnosed only during evaluation for hypogonadism and/or infertility. In February 2010 an interdisciplinary p...
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| Veröffentlicht in: | Journal of endocrinological investigation 2010-12, Vol.33 (11), p.839-850 |
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| container_title | Journal of endocrinological investigation |
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| creator | Radicioni, A. F. Ferlin, A. Balercia, G. Pasquali, D. Vignozzi, L. Maggi, M. Foresta, C. Lenzi, A. |
| description | Nearly 70 years after its description, Klinefelter syndrome (KS) remains a largely undiagnosed condition. As its clinical presentation may be subtle, many of those affected may be unaware or diagnosed only during evaluation for hypogonadism and/or infertility. In February 2010 an interdisciplinary panel of specialists met in Abano Terme (Padua, Italy) in a workshop on “Klinefelter Syndrome: diagnosis and clinical management”. The main aim of this meeting was to discuss several aspects related to the epidemiology, pathogenesis, and evaluation of KS and to develop a consensus defining its early diagnosis and treatment. In the present consensus we have highlighted the features that may prompt the physicians to look after patients with KS both for the syndrome and correlated diseases. We have provided evidences that, during the different phases of life, there might be some advantages in establishing the diagnosis and starting proper follow-up and treatment. The workshop was carried out under the auspices of the Italian Society of andrology and Sexual Medicine (SIAMS). |
| doi_str_mv | 10.1007/BF03350351 |
| format | Article |
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F. ; Ferlin, A. ; Balercia, G. ; Pasquali, D. ; Vignozzi, L. ; Maggi, M. ; Foresta, C. ; Lenzi, A.</creator><creatorcontrib>Radicioni, A. F. ; Ferlin, A. ; Balercia, G. ; Pasquali, D. ; Vignozzi, L. ; Maggi, M. ; Foresta, C. ; Lenzi, A.</creatorcontrib><description>Nearly 70 years after its description, Klinefelter syndrome (KS) remains a largely undiagnosed condition. As its clinical presentation may be subtle, many of those affected may be unaware or diagnosed only during evaluation for hypogonadism and/or infertility. In February 2010 an interdisciplinary panel of specialists met in Abano Terme (Padua, Italy) in a workshop on “Klinefelter Syndrome: diagnosis and clinical management”. The main aim of this meeting was to discuss several aspects related to the epidemiology, pathogenesis, and evaluation of KS and to develop a consensus defining its early diagnosis and treatment. In the present consensus we have highlighted the features that may prompt the physicians to look after patients with KS both for the syndrome and correlated diseases. We have provided evidences that, during the different phases of life, there might be some advantages in establishing the diagnosis and starting proper follow-up and treatment. 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F.</creatorcontrib><creatorcontrib>Ferlin, A.</creatorcontrib><creatorcontrib>Balercia, G.</creatorcontrib><creatorcontrib>Pasquali, D.</creatorcontrib><creatorcontrib>Vignozzi, L.</creatorcontrib><creatorcontrib>Maggi, M.</creatorcontrib><creatorcontrib>Foresta, C.</creatorcontrib><creatorcontrib>Lenzi, A.</creatorcontrib><title>Consensus statement on diagnosis and clinical management of Klinefelter syndrome</title><title>Journal of endocrinological investigation</title><addtitle>J Endocrinol Invest</addtitle><addtitle>J Endocrinol Invest</addtitle><description>Nearly 70 years after its description, Klinefelter syndrome (KS) remains a largely undiagnosed condition. As its clinical presentation may be subtle, many of those affected may be unaware or diagnosed only during evaluation for hypogonadism and/or infertility. In February 2010 an interdisciplinary panel of specialists met in Abano Terme (Padua, Italy) in a workshop on “Klinefelter Syndrome: diagnosis and clinical management”. The main aim of this meeting was to discuss several aspects related to the epidemiology, pathogenesis, and evaluation of KS and to develop a consensus defining its early diagnosis and treatment. In the present consensus we have highlighted the features that may prompt the physicians to look after patients with KS both for the syndrome and correlated diseases. We have provided evidences that, during the different phases of life, there might be some advantages in establishing the diagnosis and starting proper follow-up and treatment. The workshop was carried out under the auspices of the Italian Society of andrology and Sexual Medicine (SIAMS).</description><subject>Adolescent</subject><subject>Adult</subject><subject>Child</subject><subject>Cognition</subject><subject>Diabetes Mellitus - etiology</subject><subject>Endocrinology</subject><subject>Gonadal Steroid Hormones - blood</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Klinefelter Syndrome - complications</subject><subject>Klinefelter Syndrome - diagnosis</subject><subject>Klinefelter Syndrome - therapy</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Metabolic Diseases</subject><subject>Metabolic Syndrome - etiology</subject><subject>Osteoporosis - etiology</subject><subject>Puberty - physiology</subject><subject>Review Article</subject><issn>0391-4097</issn><issn>1720-8386</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpt0EFLwzAUB_AgipvTix9AchOUapLXLu1Rh1NxoAc9lyx5GR1tMpP2sG9vZFMvXvIg78cf3p-Qc85uOGPy9n7OAAoGBT8gYy4Fy0oop4dkzKDiWc4qOSInMa4ZAwmlPCYjwUUFSY7J28y7iC4OkcZe9dih66l31DRq5XxsIlXOUN02rtGqpZ1yarVHlr6kb7TY9hho3DoTfIen5MiqNuLZfk7Ix_zhffaULV4fn2d3i0yDEH2mDAc0PJ8uUS45LwthBQeGViphkVkEa83UaDE1RalRCK0BlLGVLPL0KpiQy13uJvjPAWNfd03U2LbKoR9iXeZVDqwqIcmrndTBxxjQ1pvQdCpsa87q7wLrvwITvtjHDssOzS_9aSyB6x2IaeVWGOq1H4JLp_4X9wXIcHnw</recordid><startdate>20101201</startdate><enddate>20101201</enddate><creator>Radicioni, A. 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F.</creatorcontrib><creatorcontrib>Ferlin, A.</creatorcontrib><creatorcontrib>Balercia, G.</creatorcontrib><creatorcontrib>Pasquali, D.</creatorcontrib><creatorcontrib>Vignozzi, L.</creatorcontrib><creatorcontrib>Maggi, M.</creatorcontrib><creatorcontrib>Foresta, C.</creatorcontrib><creatorcontrib>Lenzi, A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of endocrinological investigation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Radicioni, A. F.</au><au>Ferlin, A.</au><au>Balercia, G.</au><au>Pasquali, D.</au><au>Vignozzi, L.</au><au>Maggi, M.</au><au>Foresta, C.</au><au>Lenzi, A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Consensus statement on diagnosis and clinical management of Klinefelter syndrome</atitle><jtitle>Journal of endocrinological investigation</jtitle><stitle>J Endocrinol Invest</stitle><addtitle>J Endocrinol Invest</addtitle><date>2010-12-01</date><risdate>2010</risdate><volume>33</volume><issue>11</issue><spage>839</spage><epage>850</epage><pages>839-850</pages><issn>0391-4097</issn><eissn>1720-8386</eissn><abstract>Nearly 70 years after its description, Klinefelter syndrome (KS) remains a largely undiagnosed condition. As its clinical presentation may be subtle, many of those affected may be unaware or diagnosed only during evaluation for hypogonadism and/or infertility. 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| identifier | ISSN: 0391-4097 |
| ispartof | Journal of endocrinological investigation, 2010-12, Vol.33 (11), p.839-850 |
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| subjects | Adolescent Adult Child Cognition Diabetes Mellitus - etiology Endocrinology Gonadal Steroid Hormones - blood Humans Infant, Newborn Klinefelter Syndrome - complications Klinefelter Syndrome - diagnosis Klinefelter Syndrome - therapy Male Medicine Medicine & Public Health Metabolic Diseases Metabolic Syndrome - etiology Osteoporosis - etiology Puberty - physiology Review Article |
| title | Consensus statement on diagnosis and clinical management of Klinefelter syndrome |
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