Intracoronary delivery of eptifibatide with the ClearWay® RX infusion catheter

Acute coronary syndromes are caused by plaque rupture and the formation of an occlusive thrombus. Intracoronary (IC) bolus administration of eptifibatide may result in higher levels of platelet glycoprotein IIb/IIIa (GP IIb/IIIa) receptor occupancy (RO) in the local coronary bed, disaggregate thromb...

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Veröffentlicht in:	Catheterization and cardiovascular interventions 2011-02, Vol.77 (2), p.222-227
Hauptverfasser:	Deibele, Albert J., Michael Gibson, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Coronary Syndrome - diagnostic imaging Acute Coronary Syndrome - drug therapy Acute Coronary Syndrome - etiology Acute Coronary Syndrome - physiopathology acute coronary syndromes Angioplasty, Balloon, Coronary - instrumentation Catheters Coronary Angiography Coronary Artery Disease - complications Coronary Artery Disease - diagnostic imaging Coronary Artery Disease - physiopathology Coronary Artery Disease - therapy Coronary Circulation - drug effects Coronary Thrombosis - diagnostic imaging Coronary Thrombosis - drug therapy Coronary Thrombosis - etiology Coronary Thrombosis - physiopathology Drug-Eluting Stents Equipment Design GP IIb/IIIa inhibitors Humans Infusions, Parenteral local drug delivery Male Metals Microcirculation - drug effects Middle Aged Peptides - administration & dosage Platelet Aggregation Inhibitors - administration & dosage Stents Treatment Outcome
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