Novel aspects of cellular action of dipeptidyl peptidase IV/CD26

The cellular dipeptidyl peptidase IV (DPIV, E.C.3.4.14.5, CD26) is a type II membrane peptidase with various physio-logical functions. Our main knowledge on DPIV comes from studies of soluble DPIV which plays a role in regulation of glucose homeostasis by inactivation of the incretins glucagon-like...

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Veröffentlicht in:	Biological chemistry 2011-03, Vol.392 (3), p.153-168
Hauptverfasser:	Ansorge, Siegfried, Nordhoff, Karsten, Bank, Ute, Heimburg, Anke, Julius, Heiko, Breyer, Doreen, Thielitz, Anja, Reinhold, Dirk, Täger, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Catalytic Domain Cell Line cellular DPIV/CD26 central pore binding site Cytokines - metabolism Dipeptidyl Peptidase 4 - chemistry Dipeptidyl Peptidase 4 - metabolism dipeptidyl peptidase IV Dipeptidyl-Peptidase IV Inhibitors - chemistry Dipeptidyl-Peptidase IV Inhibitors - pharmacology DNA - biosynthesis Humans immune functions Lymphocytes - enzymology Models, Molecular neuropeptide Y (NPY) Neuropeptide Y - metabolism
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