Matrix Therapy with RGTA OTR4120 Improves Healing Time and Quality in Hairless Rats with Deep Second-Degree Burns

ReGeneraTing Agents (RGTAs) are biodegradable polymers engineered to mimic heparan-sulfate in the extracellular matrix of damaged tissue. RGTAs improve tissue healing in several animal models by stabilizing and protecting heparin-binding growth factors and matrix proteins. RGTA restores the normal m...

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Veröffentlicht in:	Plastic and reconstructive surgery (1963) 2011-02, Vol.127 (2), p.541-550
Hauptverfasser:	Zakine, Gilbert, Barbier, Véronique, Garcia-Filipe, Stéphanie, Luboinski, Jacqueline, Papy-Garcia, Dulce, Chachques, Juan Carlos, Carpentier, Alain, Barritault, Denis
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biomimetic Materials - therapeutic use Burns Burns - drug therapy Burns - pathology Burns - physiopathology Disease Models, Animal Epidermis - pathology Epidermis - physiology Extracellular Matrix - drug effects Female Glycosaminoglycans - pharmacology Glycosaminoglycans - therapeutic use Heparan Sulfate Proteoglycans - pharmacology Heparan Sulfate Proteoglycans - therapeutic use Keratinocytes Medical sciences Necrosis Rats Rats, Inbred Strains Regeneration - drug effects Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Traumas. Diseases due to physical agents Wound Healing - drug effects
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