Antigenic Specificities Related to the Cold Agglutinin Activity of Gamma M Globulins

Certain antiserums prepared against isolated cold agglutinins demonstrate specificity for gamma M globulins with this activity and not for similar gamma M globulins lacking such activity. The cold agglutinin specific antigens fall into several major and minor groups. Their exact relation to the pres...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1968-07, Vol.161 (3839), p.379-381
Hauptverfasser: Williams, Ralph C., Kunkel, Henry G., Capra, J. Donald
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container_issue 3839
container_start_page 379
container_title Science (American Association for the Advancement of Science)
container_volume 161
creator Williams, Ralph C.
Kunkel, Henry G.
Capra, J. Donald
description Certain antiserums prepared against isolated cold agglutinins demonstrate specificity for gamma M globulins with this activity and not for similar gamma M globulins lacking such activity. The cold agglutinin specific antigens fall into several major and minor groups. Their exact relation to the presumed antibody-combining sites remains to be determined.
doi_str_mv 10.1126/science.161.3839.379
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source MEDLINE; JSTOR Archive Collection A-Z Listing; American Association for the Advancement of Science
subjects Agglutinins
Antibodies
Antibodies - analysis
Antigen-Antibody Reactions
Antigens
Antiserum
Autoimmune Diseases
Calcium
Cold Temperature
gamma-Globulins
Globulins
Humans
Immune Sera
Immunodiffusion
Macroglobulins
Macroglobulins - analysis
Microtubule proteins
Mitotic spindle apparatus
Spermatozoa
title Antigenic Specificities Related to the Cold Agglutinin Activity of Gamma M Globulins
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