Characteristic Electrophoretic Patterns in Hemophilia and Idiopathic Thrombocytopenia.
Summary Characteristic electrophoretic patterns have been observed in all 5 cases of hemophilia and in all 8 cases of idiopathic thrombocytopenic purpura. These patterns show the following characteristics: (a) appearance of an unusual peak in the group of the α-globulins (αx), and (b) disappearance...
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Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1951-07, Vol.77 (3), p.551-553 |
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container_title | Experimental biology and medicine (Maywood, N.J.) |
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creator | Bernfeld, Peter Stefanini, Mario |
description | Summary
Characteristic electrophoretic patterns have been observed in all 5 cases of hemophilia and in all 8 cases of idiopathic thrombocytopenic purpura. These patterns show the following characteristics: (a) appearance of an unusual peak in the group of the α-globulins (αx), and (b) disappearance of the usual α2- and α3-globulin peaks. The same anomaly has been observed in some cases of secondary thrombocytopenia, “anaphylactoid” type of vascular purpura, and hemolytic anemia with evidence of platelet dysfunction. |
doi_str_mv | 10.3181/00379727-77-18846 |
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Characteristic electrophoretic patterns have been observed in all 5 cases of hemophilia and in all 8 cases of idiopathic thrombocytopenic purpura. These patterns show the following characteristics: (a) appearance of an unusual peak in the group of the α-globulins (αx), and (b) disappearance of the usual α2- and α3-globulin peaks. The same anomaly has been observed in some cases of secondary thrombocytopenia, “anaphylactoid” type of vascular purpura, and hemolytic anemia with evidence of platelet dysfunction.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-77-18846</identifier><identifier>PMID: 14864657</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Hemophilia A ; Humans ; Old Medline ; Purpura ; Purpura, Thrombocytopenic ; Purpura, Thrombocytopenic, Idiopathic ; Thrombocytopenia</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1951-07, Vol.77 (3), p.551-553</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c338t-c855641c1cb6d18e0e97ad167f0766308ade5d434da0b7431ad0e5b5c168af973</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14864657$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bernfeld, Peter</creatorcontrib><creatorcontrib>Stefanini, Mario</creatorcontrib><title>Characteristic Electrophoretic Patterns in Hemophilia and Idiopathic Thrombocytopenia.</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary
Characteristic electrophoretic patterns have been observed in all 5 cases of hemophilia and in all 8 cases of idiopathic thrombocytopenic purpura. These patterns show the following characteristics: (a) appearance of an unusual peak in the group of the α-globulins (αx), and (b) disappearance of the usual α2- and α3-globulin peaks. The same anomaly has been observed in some cases of secondary thrombocytopenia, “anaphylactoid” type of vascular purpura, and hemolytic anemia with evidence of platelet dysfunction.</description><subject>Hemophilia A</subject><subject>Humans</subject><subject>Old Medline</subject><subject>Purpura</subject><subject>Purpura, Thrombocytopenic</subject><subject>Purpura, Thrombocytopenic, Idiopathic</subject><subject>Thrombocytopenia</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1951</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kL1OwzAURi0EoqXwACwoE1uKXf9mRBXQSpVgKKyWYzvUVRIH2xn69iS0iI3p6uo795PuAeAWwTlGAj1AiHnBFzznPEdCEHYGpohimmNWFOdgOub5CEzAVYx7CBHlC3YJJogIRhjlU_Cx3KmgdLLBxeR09lRbnYLvdj7YcX9TacjamLk2W9lmCFztVKZak62N851Ku4Ha7oJvSq8PyXe2dWp-DS4qVUd7c5oz8P78tF2u8s3ry3r5uMk1xiLlWlDKCNJIl8wgYaEtuDKI8QpyxjAUylhqCCZGwZITjJSBlpZUIyZUVXA8A_fH3i74r97GJBsXta1r1VrfRymI4LxY4AFER1AHH2OwleyCa1Q4SATlKFP-ypScyx-Zw83dqbwvG2v-Lk72BmB-BKL6tHLv-9AOz_7T-A0J034M</recordid><startdate>195107</startdate><enddate>195107</enddate><creator>Bernfeld, Peter</creator><creator>Stefanini, Mario</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>195107</creationdate><title>Characteristic Electrophoretic Patterns in Hemophilia and Idiopathic Thrombocytopenia.</title><author>Bernfeld, Peter ; Stefanini, Mario</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c338t-c855641c1cb6d18e0e97ad167f0766308ade5d434da0b7431ad0e5b5c168af973</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1951</creationdate><topic>Hemophilia A</topic><topic>Humans</topic><topic>Old Medline</topic><topic>Purpura</topic><topic>Purpura, Thrombocytopenic</topic><topic>Purpura, Thrombocytopenic, Idiopathic</topic><topic>Thrombocytopenia</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bernfeld, Peter</creatorcontrib><creatorcontrib>Stefanini, Mario</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bernfeld, Peter</au><au>Stefanini, Mario</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Characteristic Electrophoretic Patterns in Hemophilia and Idiopathic Thrombocytopenia.</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1951-07</date><risdate>1951</risdate><volume>77</volume><issue>3</issue><spage>551</spage><epage>553</epage><pages>551-553</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary
Characteristic electrophoretic patterns have been observed in all 5 cases of hemophilia and in all 8 cases of idiopathic thrombocytopenic purpura. These patterns show the following characteristics: (a) appearance of an unusual peak in the group of the α-globulins (αx), and (b) disappearance of the usual α2- and α3-globulin peaks. The same anomaly has been observed in some cases of secondary thrombocytopenia, “anaphylactoid” type of vascular purpura, and hemolytic anemia with evidence of platelet dysfunction.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>14864657</pmid><doi>10.3181/00379727-77-18846</doi><tpages>3</tpages></addata></record> |
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subjects | Hemophilia A Humans Old Medline Purpura Purpura, Thrombocytopenic Purpura, Thrombocytopenic, Idiopathic Thrombocytopenia |
title | Characteristic Electrophoretic Patterns in Hemophilia and Idiopathic Thrombocytopenia. |
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