Upregulation of mammary gland OCTNs maintains carnitine homeostasis in suckling infants

► l-Carnitine transport from maternal stores into breast milk is critical for fatty acid oxidation and ketogenesis for newborn cerebral metabolism. ► No studies have shown dynamic regulation of carnitine/organic cation transporters Octn1, -2 and -3 at different mammary gland developmental stages. ►...

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Veröffentlicht in:	Biochemical and biophysical research communications 2011-01, Vol.404 (4), p.1010-1015
Hauptverfasser:	Lamhonwah, Anne-Marie, Mai, Lydia, Chung, Cilla, Lamhonwah, Daniel, Ackerley, Cameron, Tein, Ingrid
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Suckling Carnitine - metabolism Carnitine/organic cation transporter Fatty acid oxidation Female Homeostasis Infant nutrition l-Carnitine Lactation Mammary glands Mammary Glands, Animal - growth & development Mammary Glands, Animal - metabolism Mice Mice, Inbred C3H Organic Cation Transport Proteins - genetics Organic Cation Transport Proteins - metabolism Up-Regulation
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