The PTPN22 R263Q polymorphism is a risk factor for rheumatoid arthritis in Caucasian case–control samples

Objective Recently, a functional PTPN22 variant (R263Q; rs33996649) was found to be associated with systemic lupus erythematosus (SLE). This study was undertaken to analyze the influence of this polymorphism on the risk of rheumatoid arthritis (RA). Methods RA patients (n = 5,579) were recruited fro...

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Veröffentlicht in:	Arthritis & rheumatology (Hoboken, N.J.) N.J.), 2011-02, Vol.63 (2), p.365-372
Hauptverfasser:	Rodríguez‐Rodríguez, Luis, Taib, Wan Rohani Wan, Topless, Ruth, Steer, Sophia, González‐Escribano, María F., Balsa, Alejandro, Pascual‐Salcedo, Dora, González‐Gay, Miguel A., Raya, Enrique, Fernandez‐Gutierrez, Benjamín, González‐Álvaro, Isidoro, Bottini, Nunzio, Witte, Torsten, Viken, Marte K., Coenen, Marieke J. H., van Riel, Piet L. C. M., Franke, Barbara, den Heijer, Martin, Radstake, Timothy R. D. J., Wordsworth, Paul, Lie, Benedicte A., Merriman, Tony R., Martín, Javier
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Case-Control Studies Diseases of the osteoarticular system European Continental Ancestry Group - genetics Female Genetic Predisposition to Disease Genotype Humans Inflammatory joint diseases Male Medical sciences Polymorphism, Single Nucleotide Protein Tyrosine Phosphatase, Non-Receptor Type 22 - genetics
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