Normal Blood Calcium Homeostasis in Response to Calcium Infusion in Pseudohypoparathyroidism and Idiopathic Hypoparathyroidism
Summary Blood calcium homeostasis after calcium infusion was measured in 4 pseudohypoparathyroid patients and in one patient with “idiopathic hypoparathyroidism”—as a reflection of possible excessive thyrocalcitonin secretion. The response was similar to that of normal subjects, and in no patient di...
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| Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1968-05, Vol.128 (1), p.9-11 |
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| container_title | Experimental biology and medicine (Maywood, N.J.) |
| container_volume | 128 |
| creator | Gershberg, Herbert Hecht, Arthur |
| description | Summary
Blood calcium homeostasis after calcium infusion was measured in 4 pseudohypoparathyroid patients and in one patient with “idiopathic hypoparathyroidism”—as a reflection of possible excessive thyrocalcitonin secretion. The response was similar to that of normal subjects, and in no patient did the postinfusion level fall below the initial level. This is evidence against the concept that excessive thyrocalcitonin secretion produces the hypocalcemia in these diseases. |
| doi_str_mv | 10.3181/00379727-128-32930 |
| format | Article |
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Blood calcium homeostasis after calcium infusion was measured in 4 pseudohypoparathyroid patients and in one patient with “idiopathic hypoparathyroidism”—as a reflection of possible excessive thyrocalcitonin secretion. The response was similar to that of normal subjects, and in no patient did the postinfusion level fall below the initial level. This is evidence against the concept that excessive thyrocalcitonin secretion produces the hypocalcemia in these diseases.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-128-32930</identifier><identifier>PMID: 5656724</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Adult ; Aged ; Calcitonin - metabolism ; Calcium - blood ; Calcium - metabolism ; Child ; Female ; Gluconates ; Homeostasis ; Humans ; Hypocalcemia - etiology ; Hypoparathyroidism - blood ; Male ; Pseudohypoparathyroidism - blood</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1968-05, Vol.128 (1), p.9-11</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5656724$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gershberg, Herbert</creatorcontrib><creatorcontrib>Hecht, Arthur</creatorcontrib><title>Normal Blood Calcium Homeostasis in Response to Calcium Infusion in Pseudohypoparathyroidism and Idiopathic Hypoparathyroidism</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary
Blood calcium homeostasis after calcium infusion was measured in 4 pseudohypoparathyroid patients and in one patient with “idiopathic hypoparathyroidism”—as a reflection of possible excessive thyrocalcitonin secretion. The response was similar to that of normal subjects, and in no patient did the postinfusion level fall below the initial level. This is evidence against the concept that excessive thyrocalcitonin secretion produces the hypocalcemia in these diseases.</description><subject>Adult</subject><subject>Aged</subject><subject>Calcitonin - metabolism</subject><subject>Calcium - blood</subject><subject>Calcium - metabolism</subject><subject>Child</subject><subject>Female</subject><subject>Gluconates</subject><subject>Homeostasis</subject><subject>Humans</subject><subject>Hypocalcemia - etiology</subject><subject>Hypoparathyroidism - blood</subject><subject>Male</subject><subject>Pseudohypoparathyroidism - blood</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1968</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1rGzEQhkVJSN20fyAQ0Cm3rfURraRja9LaEJoQ2rOQpdlaYXe11ewefOlvz7p2cyn0NDDvMy_MQ8gVZx8lN3zJmNRWC11xYSoprGRvyIIrqSpZW3tGFgegOhBvyTvEZ8a40qK-IBeqVrUWtwvy-1sunW_p5zbnSFe-DWnq6Dp3kHH0mJCmnj4BDrlHoGN-RTZ9M2HK_SF_RJhi3u2HPPjix92-5BQTdtT3kW5imtfjLgW6_od4T84b3yJ8OM1L8uPL3ffVurp_-LpZfbqvgjB2rJSxEbbbrfbQ1NYoCNEzIYPiUc5PgQEBUnEG2nqhmAmhltL6RvKGa2W9vCQ3x96h5F8T4Oi6hAHa1veQJ3Tm1tTaWDmD4giGkhELNG4oqfNl7zhzB-nur3Q3S3d_pM9H16f2adtBfD05WZ7z5TFH_xPcc55KPz_7v8YXtGqNmg</recordid><startdate>196805</startdate><enddate>196805</enddate><creator>Gershberg, Herbert</creator><creator>Hecht, Arthur</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196805</creationdate><title>Normal Blood Calcium Homeostasis in Response to Calcium Infusion in Pseudohypoparathyroidism and Idiopathic Hypoparathyroidism</title><author>Gershberg, Herbert ; Hecht, Arthur</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c289t-589debbb7aef6985ecda023c51d3001e8e2e3510e79a2508cc6339af31f1759a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1968</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Calcitonin - metabolism</topic><topic>Calcium - blood</topic><topic>Calcium - metabolism</topic><topic>Child</topic><topic>Female</topic><topic>Gluconates</topic><topic>Homeostasis</topic><topic>Humans</topic><topic>Hypocalcemia - etiology</topic><topic>Hypoparathyroidism - blood</topic><topic>Male</topic><topic>Pseudohypoparathyroidism - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gershberg, Herbert</creatorcontrib><creatorcontrib>Hecht, Arthur</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gershberg, Herbert</au><au>Hecht, Arthur</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Normal Blood Calcium Homeostasis in Response to Calcium Infusion in Pseudohypoparathyroidism and Idiopathic Hypoparathyroidism</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1968-05</date><risdate>1968</risdate><volume>128</volume><issue>1</issue><spage>9</spage><epage>11</epage><pages>9-11</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary
Blood calcium homeostasis after calcium infusion was measured in 4 pseudohypoparathyroid patients and in one patient with “idiopathic hypoparathyroidism”—as a reflection of possible excessive thyrocalcitonin secretion. The response was similar to that of normal subjects, and in no patient did the postinfusion level fall below the initial level. This is evidence against the concept that excessive thyrocalcitonin secretion produces the hypocalcemia in these diseases.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>5656724</pmid><doi>10.3181/00379727-128-32930</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0037-9727 |
| ispartof | Experimental biology and medicine (Maywood, N.J.), 1968-05, Vol.128 (1), p.9-11 |
| issn | 0037-9727 1535-3702 1535-3699 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_84867893 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adult Aged Calcitonin - metabolism Calcium - blood Calcium - metabolism Child Female Gluconates Homeostasis Humans Hypocalcemia - etiology Hypoparathyroidism - blood Male Pseudohypoparathyroidism - blood |
| title | Normal Blood Calcium Homeostasis in Response to Calcium Infusion in Pseudohypoparathyroidism and Idiopathic Hypoparathyroidism |
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