Free and peptide hydroxyproline in chronic uremia
Plasma levels, urinary excretion and renal clearance rates of free and peptide hydroxyproline were estimated in normal subjects, patients with chronic uremia, and in representative cases of generalised bone disease and chronic pyelonephritis without glomerular insufficiency. Chronic uremia was accom...
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| Veröffentlicht in: | Clinica chimica acta 1968-03, Vol.19 (3), p.387-390 |
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| container_title | Clinica chimica acta |
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| creator | Dubovský, J. Dubovská, Eva Pacovský, V. Hrba, J. |
| description | Plasma levels, urinary excretion and renal clearance rates of free and peptide hydroxyproline were estimated in normal subjects, patients with chronic uremia, and in representative cases of generalised bone disease and chronic pyelonephritis without glomerular insufficiency. Chronic uremia was accompanied by an elevation of plasma levels and urinary excretion of free hydroxyproline, whereas the excretion of hydroxyproline peptides was decreased despite increased plasma levels. The changes of free hydroxyproline appeared to be related to the degree of glomerular insufficiency. |
| doi_str_mv | 10.1016/0009-8981(68)90263-5 |
| format | Article |
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Chronic uremia was accompanied by an elevation of plasma levels and urinary excretion of free hydroxyproline, whereas the excretion of hydroxyproline peptides was decreased despite increased plasma levels. 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Chronic uremia was accompanied by an elevation of plasma levels and urinary excretion of free hydroxyproline, whereas the excretion of hydroxyproline peptides was decreased despite increased plasma levels. The changes of free hydroxyproline appeared to be related to the degree of glomerular insufficiency.</description><subject>Bone Diseases - metabolism</subject><subject>Chronic Disease</subject><subject>Hydroxyproline - blood</subject><subject>Hydroxyproline - metabolism</subject><subject>Hydroxyproline - urine</subject><subject>Kidney Function Tests</subject><subject>Kidney Glomerulus - physiopathology</subject><subject>Peptides - metabolism</subject><subject>Pyelonephritis - metabolism</subject><subject>Uremia - metabolism</subject><issn>0009-8981</issn><issn>1873-3492</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1968</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1Lw0AQhhdRaq3-A4WcRA_Rnewm2VwEKVaFghc9L8nshK7ky91E7L83saVHTzPD-87Xw9gl8DvgkNxzzrNQZQpuEnWb8SgRYXzE5qBSEQqZRcdsfrCcsjPvP8dS8gRmbBYnUgiezBmsHFGQNyboqOutoWCzNa792XaurWxDgW0C3Li2sRgMjmqbn7OTMq88Xezjgn2snt6XL-H67fl1-bgOUcRpH4LghYAIhFAYZYgFKsmlKLjAMjNpLFIRGYzLIuOoMCEOlHOp8hTGFFIjFux6N3e85Gsg3-vaeqSqyhtqB6-VVBIkxKNR7ozoWu8dlbpzts7dVgPXEyk9YdATBp0o_UdKT21X-_lDUZM5NO3RjPrDTqfxyW9LTnu01CAZ6wh7bVr7_4Jf2EJ2PA</recordid><startdate>196803</startdate><enddate>196803</enddate><creator>Dubovský, J.</creator><creator>Dubovská, Eva</creator><creator>Pacovský, V.</creator><creator>Hrba, J.</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196803</creationdate><title>Free and peptide hydroxyproline in chronic uremia</title><author>Dubovský, J. ; Dubovská, Eva ; Pacovský, V. ; Hrba, J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-130b3121338c29ccbc84043b03cf9d753732dc5fb90c8c6e01ea048a71e0117d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1968</creationdate><topic>Bone Diseases - metabolism</topic><topic>Chronic Disease</topic><topic>Hydroxyproline - blood</topic><topic>Hydroxyproline - metabolism</topic><topic>Hydroxyproline - urine</topic><topic>Kidney Function Tests</topic><topic>Kidney Glomerulus - physiopathology</topic><topic>Peptides - metabolism</topic><topic>Pyelonephritis - metabolism</topic><topic>Uremia - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dubovský, J.</creatorcontrib><creatorcontrib>Dubovská, Eva</creatorcontrib><creatorcontrib>Pacovský, V.</creatorcontrib><creatorcontrib>Hrba, J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinica chimica acta</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dubovský, J.</au><au>Dubovská, Eva</au><au>Pacovský, V.</au><au>Hrba, J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Free and peptide hydroxyproline in chronic uremia</atitle><jtitle>Clinica chimica acta</jtitle><addtitle>Clin Chim Acta</addtitle><date>1968-03</date><risdate>1968</risdate><volume>19</volume><issue>3</issue><spage>387</spage><epage>390</epage><pages>387-390</pages><issn>0009-8981</issn><eissn>1873-3492</eissn><abstract>Plasma levels, urinary excretion and renal clearance rates of free and peptide hydroxyproline were estimated in normal subjects, patients with chronic uremia, and in representative cases of generalised bone disease and chronic pyelonephritis without glomerular insufficiency. 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| fulltext | fulltext |
| identifier | ISSN: 0009-8981 |
| ispartof | Clinica chimica acta, 1968-03, Vol.19 (3), p.387-390 |
| issn | 0009-8981 1873-3492 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_84841415 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Bone Diseases - metabolism Chronic Disease Hydroxyproline - blood Hydroxyproline - metabolism Hydroxyproline - urine Kidney Function Tests Kidney Glomerulus - physiopathology Peptides - metabolism Pyelonephritis - metabolism Uremia - metabolism |
| title | Free and peptide hydroxyproline in chronic uremia |
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