Biological Activity of Alkali Treated Aureomycin
Summary Alkali treated Streptomyces aureojaciens fermentation liquor contained considerable unchanged aureomycin. The pure antibiotic is inactivated by similar treatment. The product arising from mild alkaline inactivation of aureomycin was isolated and found to have essentially no antibacterial act...
Gespeichert in:
| Veröffentlicht in: | Experimental biology and medicine (Maywood, N.J.) N.J.), 1951-04, Vol.76 (4), p.676-679 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 679 |
|---|---|
| container_issue | 4 |
| container_start_page | 676 |
| container_title | Experimental biology and medicine (Maywood, N.J.) |
| container_volume | 76 |
| creator | Dornbush, A. C. Oleson, J. J. Whitehill, A. L. Hutchings, B. L. |
| description | Summary
Alkali treated Streptomyces aureojaciens fermentation liquor contained considerable unchanged aureomycin. The pure antibiotic is inactivated by similar treatment. The product arising from mild alkaline inactivation of aureomycin was isolated and found to have essentially no antibacterial activity and no growth stimulating activity for the chick. |
| doi_str_mv | 10.3181/00379727-76-18592 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_84836702</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.3181_00379727-76-18592</sage_id><sourcerecordid>84836702</sourcerecordid><originalsourceid>FETCH-LOGICAL-c338t-6ddc1175a568e1f90628b962a4a12706f1e5a0c8a38a3d4fc6e075315dfa82b53</originalsourceid><addsrcrecordid>eNp9kE1LAzEQhoMotlZ_gBfZk7etmWTzsce11A8oeKnnkGazJTXb1GRX6L93ayvehIE5zPO-MA9Ct4CnFCQ8YExFKYjIBc9BspKcoTEwynLKy_IcjQ_3_ACM0FVKG4yBCcIv0QgKWRQUl2OEH13wYe2M9lllOvflun0WmqzyH9q7bBmt7mydVX20od0bt71GF432yd6c9gS9P82Xs5d88fb8OqsWuaFUdjmvawMgmGZcWmhKzIlclZzoQgMRmDdgmcZGajpMXTSGWywYBVY3WpIVoxN0f-zdxfDZ29Sp1iVjvddbG_qkZCEpF5gMIBxBE0NK0TZqF12r414BVgdN6leTElz9aBoyd6fyftXa-i9x8jIA0yOQ9NqqTejjdnj2n8ZvUXxulQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>84836702</pqid></control><display><type>article</type><title>Biological Activity of Alkali Treated Aureomycin</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Dornbush, A. C. ; Oleson, J. J. ; Whitehill, A. L. ; Hutchings, B. L.</creator><creatorcontrib>Dornbush, A. C. ; Oleson, J. J. ; Whitehill, A. L. ; Hutchings, B. L.</creatorcontrib><description>Summary
Alkali treated Streptomyces aureojaciens fermentation liquor contained considerable unchanged aureomycin. The pure antibiotic is inactivated by similar treatment. The product arising from mild alkaline inactivation of aureomycin was isolated and found to have essentially no antibacterial activity and no growth stimulating activity for the chick.</description><identifier>ISSN: 0037-9727</identifier><identifier>ISSN: 1535-3702</identifier><identifier>EISSN: 1535-3699</identifier><identifier>DOI: 10.3181/00379727-76-18592</identifier><identifier>PMID: 14844309</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Alkalies ; Chlortetracycline ; Old Medline</subject><ispartof>Experimental biology and medicine (Maywood, N.J.), 1951-04, Vol.76 (4), p.676-679</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c338t-6ddc1175a568e1f90628b962a4a12706f1e5a0c8a38a3d4fc6e075315dfa82b53</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14844309$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dornbush, A. C.</creatorcontrib><creatorcontrib>Oleson, J. J.</creatorcontrib><creatorcontrib>Whitehill, A. L.</creatorcontrib><creatorcontrib>Hutchings, B. L.</creatorcontrib><title>Biological Activity of Alkali Treated Aureomycin</title><title>Experimental biology and medicine (Maywood, N.J.)</title><addtitle>Proc Soc Exp Biol Med</addtitle><description>Summary
Alkali treated Streptomyces aureojaciens fermentation liquor contained considerable unchanged aureomycin. The pure antibiotic is inactivated by similar treatment. The product arising from mild alkaline inactivation of aureomycin was isolated and found to have essentially no antibacterial activity and no growth stimulating activity for the chick.</description><subject>Alkalies</subject><subject>Chlortetracycline</subject><subject>Old Medline</subject><issn>0037-9727</issn><issn>1535-3702</issn><issn>1535-3699</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1951</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LAzEQhoMotlZ_gBfZk7etmWTzsce11A8oeKnnkGazJTXb1GRX6L93ayvehIE5zPO-MA9Ct4CnFCQ8YExFKYjIBc9BspKcoTEwynLKy_IcjQ_3_ACM0FVKG4yBCcIv0QgKWRQUl2OEH13wYe2M9lllOvflun0WmqzyH9q7bBmt7mydVX20od0bt71GF432yd6c9gS9P82Xs5d88fb8OqsWuaFUdjmvawMgmGZcWmhKzIlclZzoQgMRmDdgmcZGajpMXTSGWywYBVY3WpIVoxN0f-zdxfDZ29Sp1iVjvddbG_qkZCEpF5gMIBxBE0NK0TZqF12r414BVgdN6leTElz9aBoyd6fyftXa-i9x8jIA0yOQ9NqqTejjdnj2n8ZvUXxulQ</recordid><startdate>195104</startdate><enddate>195104</enddate><creator>Dornbush, A. C.</creator><creator>Oleson, J. J.</creator><creator>Whitehill, A. L.</creator><creator>Hutchings, B. L.</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>195104</creationdate><title>Biological Activity of Alkali Treated Aureomycin</title><author>Dornbush, A. C. ; Oleson, J. J. ; Whitehill, A. L. ; Hutchings, B. L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c338t-6ddc1175a568e1f90628b962a4a12706f1e5a0c8a38a3d4fc6e075315dfa82b53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1951</creationdate><topic>Alkalies</topic><topic>Chlortetracycline</topic><topic>Old Medline</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dornbush, A. C.</creatorcontrib><creatorcontrib>Oleson, J. J.</creatorcontrib><creatorcontrib>Whitehill, A. L.</creatorcontrib><creatorcontrib>Hutchings, B. L.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dornbush, A. C.</au><au>Oleson, J. J.</au><au>Whitehill, A. L.</au><au>Hutchings, B. L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Biological Activity of Alkali Treated Aureomycin</atitle><jtitle>Experimental biology and medicine (Maywood, N.J.)</jtitle><addtitle>Proc Soc Exp Biol Med</addtitle><date>1951-04</date><risdate>1951</risdate><volume>76</volume><issue>4</issue><spage>676</spage><epage>679</epage><pages>676-679</pages><issn>0037-9727</issn><issn>1535-3702</issn><eissn>1535-3699</eissn><abstract>Summary
Alkali treated Streptomyces aureojaciens fermentation liquor contained considerable unchanged aureomycin. The pure antibiotic is inactivated by similar treatment. The product arising from mild alkaline inactivation of aureomycin was isolated and found to have essentially no antibacterial activity and no growth stimulating activity for the chick.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>14844309</pmid><doi>10.3181/00379727-76-18592</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0037-9727 |
| ispartof | Experimental biology and medicine (Maywood, N.J.), 1951-04, Vol.76 (4), p.676-679 |
| issn | 0037-9727 1535-3702 1535-3699 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_84836702 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Alkalies Chlortetracycline Old Medline |
| title | Biological Activity of Alkali Treated Aureomycin |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-26T14%3A05%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Biological%20Activity%20of%20Alkali%20Treated%20Aureomycin&rft.jtitle=Experimental%20biology%20and%20medicine%20(Maywood,%20N.J.)&rft.au=Dornbush,%20A.%20C.&rft.date=1951-04&rft.volume=76&rft.issue=4&rft.spage=676&rft.epage=679&rft.pages=676-679&rft.issn=0037-9727&rft.eissn=1535-3699&rft_id=info:doi/10.3181/00379727-76-18592&rft_dat=%3Cproquest_cross%3E84836702%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=84836702&rft_id=info:pmid/14844309&rft_sage_id=10.3181_00379727-76-18592&rfr_iscdi=true |