Voluntary running, skeletal muscle gene expression, and signaling inversely regulated by orchidectomy and testosterone replacement

Declines in skeletal muscle size and strength, often seen with chronic wasting diseases, prolonged or high-dose glucocorticoid therapy, and the natural aging process in mammals, are usually associated with reduced physical activity and testosterone levels. However, it is not clear whether the declin...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology: endocrinology and metabolism 2011-02, Vol.300 (2), p.E327-E340
Hauptverfasser:	Ibebunjo, Chikwendu, Eash, John K, Li, Christine, Ma, QiCheng, Glass, David J
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Anatomy, Cross-Sectional Animals Blotting, Western Body Weight - physiology Chronic diseases Eating Endurance Energy Metabolism - drug effects Energy Metabolism - physiology Exercise Gene expression Gene Expression - physiology Insulin-Like Growth Factor I - biosynthesis Insulin-Like Growth Factor I - genetics Male Metabolism Mice Mice, Inbred C57BL Microarray Analysis Motor Activity - physiology Muscle Fibers, Skeletal - physiology Muscle, Skeletal - anatomy & histology Muscle, Skeletal - cytology Muscle, Skeletal - metabolism Muscles (size) Musculoskeletal system Orchiectomy Organ Size - physiology Physical Endurance - physiology Reverse Transcriptase Polymerase Chain Reaction RNA - biosynthesis RNA - genetics Rodents Running Running - physiology Signal Transduction - physiology Speed Testosterone Testosterone - blood Testosterone - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!