Regulation of muscular glutamate metabolism by high-protein diet in broiler chicks
The major taste active component, glutamate (Glu), improves the taste of meat. In this study, we investigated the effect of a short-term high-protein (HCP) diet on the intramuscular free Glu content to improve the taste of meat. Furthermore, we elucidated how the muscle free Glu content was controll...
Gespeichert in:
| Veröffentlicht in: | Animal science journal 2011-02, Vol.82 (1), p.86-92 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 92 |
|---|---|
| container_issue | 1 |
| container_start_page | 86 |
| container_title | Animal science journal |
| container_volume | 82 |
| creator | Kobayashi, Hiroyuki Eguchi, Atsushi Takano, Wataru Shibata, Masahiro Kadowaki, Motoni Fujimura, Shinobu |
| description | The major taste active component, glutamate (Glu), improves the taste of meat. In this study, we investigated the effect of a short-term high-protein (HCP) diet on the intramuscular free Glu content to improve the taste of meat. Furthermore, we elucidated how the muscle free Glu content was controlled by the HCP diet. Chicks (14 days old) were fed the control diet or HCP diet for 10 days. Plasma and muscle free amino acid concentrations, and activity and messenger RNA (mRNA) expression of muscle enzymes related to Glu metabolism were determined. Muscle free Glu content was increased (P < 0.01) by 51%. Activity and mRNA expression of glutaminase (GA), which is one of the major Glu-related enzymes, were significantly decreased (P < 0.05) in the HCP group because of feedback inhibition. The mRNA expression of lysine α-ketoglutarate reductase (LKR), which is the enzyme involved in lysine (Lys) degradation and Glu production, was significantly increased (P < 0.001) in the HCP group. These results suggest that short-term dietary HCP feeding is an effective treatment for improving the taste of meat. Furthermore, our results suggest that the free Glu content in muscle is regulated by GA and LKR. |
| doi_str_mv | 10.1111/j.1740-0929.2010.00811.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_848313023</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2250068341</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5511-dd898adb0cb4198303e56f27493a68174b0719e4e3b126e81aa470e90b29531f3</originalsourceid><addsrcrecordid>eNqNkE9v1DAQxS0EoqXwFcDiwinL-F9iS1yqFWxbKkAtFdwsJ3F2vU02xU7E7rfvLGn30BO-zIz9e0_jRwhlMGN4Pq5nrJCQgeFmxgFvATRjs-0zcnx4eI69kDITRrIj8iqlNQArDKiX5IgznhuRq2NydeWXY-uG0G9o39BuTBWOkS7bcXCdGzzt_ODKvg2po-WOrsJyld3FfvBhQ-vgB4q1jH1ofaTVKlS36TV50bg2-TcP9YTcfPn8c36WXX5fnM9PL7NKKcayutZGu7qEqpTMaAHCq7zhhTTC5Rq_UULBjJdelLit18w5WYA3UHKjBGvECfkw-eI6f0afBtuFVPm2dRvfj8lqqQUTwAWS75-Q636MG1wOoUIJzpVESE9QFfuUom_sXQydizvLwO5Tt2u7D9fuw7X71O2_1O0WpW8f_Mey8_VB-BgzAp8m4C_mtPtvY3t6fYENyrNJHtLgtwe5i7c2L0Sh7K9vC5vL_Pecf_1hF8i_m_jG9dYtY0j25hqNJQAILnUu7gGI_abb</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>847532254</pqid></control><display><type>article</type><title>Regulation of muscular glutamate metabolism by high-protein diet in broiler chicks</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><source>Alma/SFX Local Collection</source><creator>Kobayashi, Hiroyuki ; Eguchi, Atsushi ; Takano, Wataru ; Shibata, Masahiro ; Kadowaki, Motoni ; Fujimura, Shinobu</creator><creatorcontrib>Kobayashi, Hiroyuki ; Eguchi, Atsushi ; Takano, Wataru ; Shibata, Masahiro ; Kadowaki, Motoni ; Fujimura, Shinobu</creatorcontrib><description>The major taste active component, glutamate (Glu), improves the taste of meat. In this study, we investigated the effect of a short-term high-protein (HCP) diet on the intramuscular free Glu content to improve the taste of meat. Furthermore, we elucidated how the muscle free Glu content was controlled by the HCP diet. Chicks (14 days old) were fed the control diet or HCP diet for 10 days. Plasma and muscle free amino acid concentrations, and activity and messenger RNA (mRNA) expression of muscle enzymes related to Glu metabolism were determined. Muscle free Glu content was increased (P < 0.01) by 51%. Activity and mRNA expression of glutaminase (GA), which is one of the major Glu-related enzymes, were significantly decreased (P < 0.05) in the HCP group because of feedback inhibition. The mRNA expression of lysine α-ketoglutarate reductase (LKR), which is the enzyme involved in lysine (Lys) degradation and Glu production, was significantly increased (P < 0.001) in the HCP group. These results suggest that short-term dietary HCP feeding is an effective treatment for improving the taste of meat. Furthermore, our results suggest that the free Glu content in muscle is regulated by GA and LKR.</description><identifier>ISSN: 1344-3941</identifier><identifier>EISSN: 1740-0929</identifier><identifier>DOI: 10.1111/j.1740-0929.2010.00811.x</identifier><identifier>PMID: 21269365</identifier><language>eng</language><publisher>Melbourne, Australia: Blackwell Publishing Asia</publisher><subject>amino acid ; amino acid composition ; Animal Feed ; Animal Nutritional Physiological Phenomena - physiology ; Animal sciences ; Animals ; broiler chickens ; Chickens - growth & development ; Chickens - metabolism ; chicks ; diet ; Diet - veterinary ; Dietary Proteins - administration & dosage ; Enzymes ; gene expression ; Glutamate Dehydrogenase - metabolism ; Glutamate-Ammonia Ligase - metabolism ; glutamic acid ; Glutamic Acid - metabolism ; Glutaminase - metabolism ; high protein diet ; meat ; messenger RNA ; Metabolism ; muscle ; Muscles - enzymology ; Muscles - metabolism ; Muscular system ; Poultry ; Proteins ; taste</subject><ispartof>Animal science journal, 2011-02, Vol.82 (1), p.86-92</ispartof><rights>2010 The Authors. Journal compilation © 2010 Japanese Society of Animal Science</rights><rights>2010 The Authors. Journal compilation © 2010 Japanese Society of Animal Science.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5511-dd898adb0cb4198303e56f27493a68174b0719e4e3b126e81aa470e90b29531f3</citedby><cites>FETCH-LOGICAL-c5511-dd898adb0cb4198303e56f27493a68174b0719e4e3b126e81aa470e90b29531f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1740-0929.2010.00811.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1740-0929.2010.00811.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1413,27906,27907,45556,45557</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21269365$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kobayashi, Hiroyuki</creatorcontrib><creatorcontrib>Eguchi, Atsushi</creatorcontrib><creatorcontrib>Takano, Wataru</creatorcontrib><creatorcontrib>Shibata, Masahiro</creatorcontrib><creatorcontrib>Kadowaki, Motoni</creatorcontrib><creatorcontrib>Fujimura, Shinobu</creatorcontrib><title>Regulation of muscular glutamate metabolism by high-protein diet in broiler chicks</title><title>Animal science journal</title><addtitle>Anim Sci J</addtitle><description>The major taste active component, glutamate (Glu), improves the taste of meat. In this study, we investigated the effect of a short-term high-protein (HCP) diet on the intramuscular free Glu content to improve the taste of meat. Furthermore, we elucidated how the muscle free Glu content was controlled by the HCP diet. Chicks (14 days old) were fed the control diet or HCP diet for 10 days. Plasma and muscle free amino acid concentrations, and activity and messenger RNA (mRNA) expression of muscle enzymes related to Glu metabolism were determined. Muscle free Glu content was increased (P < 0.01) by 51%. Activity and mRNA expression of glutaminase (GA), which is one of the major Glu-related enzymes, were significantly decreased (P < 0.05) in the HCP group because of feedback inhibition. The mRNA expression of lysine α-ketoglutarate reductase (LKR), which is the enzyme involved in lysine (Lys) degradation and Glu production, was significantly increased (P < 0.001) in the HCP group. These results suggest that short-term dietary HCP feeding is an effective treatment for improving the taste of meat. Furthermore, our results suggest that the free Glu content in muscle is regulated by GA and LKR.</description><subject>amino acid</subject><subject>amino acid composition</subject><subject>Animal Feed</subject><subject>Animal Nutritional Physiological Phenomena - physiology</subject><subject>Animal sciences</subject><subject>Animals</subject><subject>broiler chickens</subject><subject>Chickens - growth & development</subject><subject>Chickens - metabolism</subject><subject>chicks</subject><subject>diet</subject><subject>Diet - veterinary</subject><subject>Dietary Proteins - administration & dosage</subject><subject>Enzymes</subject><subject>gene expression</subject><subject>Glutamate Dehydrogenase - metabolism</subject><subject>Glutamate-Ammonia Ligase - metabolism</subject><subject>glutamic acid</subject><subject>Glutamic Acid - metabolism</subject><subject>Glutaminase - metabolism</subject><subject>high protein diet</subject><subject>meat</subject><subject>messenger RNA</subject><subject>Metabolism</subject><subject>muscle</subject><subject>Muscles - enzymology</subject><subject>Muscles - metabolism</subject><subject>Muscular system</subject><subject>Poultry</subject><subject>Proteins</subject><subject>taste</subject><issn>1344-3941</issn><issn>1740-0929</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE9v1DAQxS0EoqXwFcDiwinL-F9iS1yqFWxbKkAtFdwsJ3F2vU02xU7E7rfvLGn30BO-zIz9e0_jRwhlMGN4Pq5nrJCQgeFmxgFvATRjs-0zcnx4eI69kDITRrIj8iqlNQArDKiX5IgznhuRq2NydeWXY-uG0G9o39BuTBWOkS7bcXCdGzzt_ODKvg2po-WOrsJyld3FfvBhQ-vgB4q1jH1ofaTVKlS36TV50bg2-TcP9YTcfPn8c36WXX5fnM9PL7NKKcayutZGu7qEqpTMaAHCq7zhhTTC5Rq_UULBjJdelLit18w5WYA3UHKjBGvECfkw-eI6f0afBtuFVPm2dRvfj8lqqQUTwAWS75-Q636MG1wOoUIJzpVESE9QFfuUom_sXQydizvLwO5Tt2u7D9fuw7X71O2_1O0WpW8f_Mey8_VB-BgzAp8m4C_mtPtvY3t6fYENyrNJHtLgtwe5i7c2L0Sh7K9vC5vL_Pecf_1hF8i_m_jG9dYtY0j25hqNJQAILnUu7gGI_abb</recordid><startdate>201102</startdate><enddate>201102</enddate><creator>Kobayashi, Hiroyuki</creator><creator>Eguchi, Atsushi</creator><creator>Takano, Wataru</creator><creator>Shibata, Masahiro</creator><creator>Kadowaki, Motoni</creator><creator>Fujimura, Shinobu</creator><general>Blackwell Publishing Asia</general><general>Blackwell Publishing Ltd</general><scope>FBQ</scope><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7T7</scope><scope>7TK</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>201102</creationdate><title>Regulation of muscular glutamate metabolism by high-protein diet in broiler chicks</title><author>Kobayashi, Hiroyuki ; Eguchi, Atsushi ; Takano, Wataru ; Shibata, Masahiro ; Kadowaki, Motoni ; Fujimura, Shinobu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5511-dd898adb0cb4198303e56f27493a68174b0719e4e3b126e81aa470e90b29531f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>amino acid</topic><topic>amino acid composition</topic><topic>Animal Feed</topic><topic>Animal Nutritional Physiological Phenomena - physiology</topic><topic>Animal sciences</topic><topic>Animals</topic><topic>broiler chickens</topic><topic>Chickens - growth & development</topic><topic>Chickens - metabolism</topic><topic>chicks</topic><topic>diet</topic><topic>Diet - veterinary</topic><topic>Dietary Proteins - administration & dosage</topic><topic>Enzymes</topic><topic>gene expression</topic><topic>Glutamate Dehydrogenase - metabolism</topic><topic>Glutamate-Ammonia Ligase - metabolism</topic><topic>glutamic acid</topic><topic>Glutamic Acid - metabolism</topic><topic>Glutaminase - metabolism</topic><topic>high protein diet</topic><topic>meat</topic><topic>messenger RNA</topic><topic>Metabolism</topic><topic>muscle</topic><topic>Muscles - enzymology</topic><topic>Muscles - metabolism</topic><topic>Muscular system</topic><topic>Poultry</topic><topic>Proteins</topic><topic>taste</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kobayashi, Hiroyuki</creatorcontrib><creatorcontrib>Eguchi, Atsushi</creatorcontrib><creatorcontrib>Takano, Wataru</creatorcontrib><creatorcontrib>Shibata, Masahiro</creatorcontrib><creatorcontrib>Kadowaki, Motoni</creatorcontrib><creatorcontrib>Fujimura, Shinobu</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Animal science journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kobayashi, Hiroyuki</au><au>Eguchi, Atsushi</au><au>Takano, Wataru</au><au>Shibata, Masahiro</au><au>Kadowaki, Motoni</au><au>Fujimura, Shinobu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Regulation of muscular glutamate metabolism by high-protein diet in broiler chicks</atitle><jtitle>Animal science journal</jtitle><addtitle>Anim Sci J</addtitle><date>2011-02</date><risdate>2011</risdate><volume>82</volume><issue>1</issue><spage>86</spage><epage>92</epage><pages>86-92</pages><issn>1344-3941</issn><eissn>1740-0929</eissn><abstract>The major taste active component, glutamate (Glu), improves the taste of meat. In this study, we investigated the effect of a short-term high-protein (HCP) diet on the intramuscular free Glu content to improve the taste of meat. Furthermore, we elucidated how the muscle free Glu content was controlled by the HCP diet. Chicks (14 days old) were fed the control diet or HCP diet for 10 days. Plasma and muscle free amino acid concentrations, and activity and messenger RNA (mRNA) expression of muscle enzymes related to Glu metabolism were determined. Muscle free Glu content was increased (P < 0.01) by 51%. Activity and mRNA expression of glutaminase (GA), which is one of the major Glu-related enzymes, were significantly decreased (P < 0.05) in the HCP group because of feedback inhibition. The mRNA expression of lysine α-ketoglutarate reductase (LKR), which is the enzyme involved in lysine (Lys) degradation and Glu production, was significantly increased (P < 0.001) in the HCP group. These results suggest that short-term dietary HCP feeding is an effective treatment for improving the taste of meat. Furthermore, our results suggest that the free Glu content in muscle is regulated by GA and LKR.</abstract><cop>Melbourne, Australia</cop><pub>Blackwell Publishing Asia</pub><pmid>21269365</pmid><doi>10.1111/j.1740-0929.2010.00811.x</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1344-3941 |
| ispartof | Animal science journal, 2011-02, Vol.82 (1), p.86-92 |
| issn | 1344-3941 1740-0929 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_848313023 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete; Alma/SFX Local Collection |
| subjects | amino acid amino acid composition Animal Feed Animal Nutritional Physiological Phenomena - physiology Animal sciences Animals broiler chickens Chickens - growth & development Chickens - metabolism chicks diet Diet - veterinary Dietary Proteins - administration & dosage Enzymes gene expression Glutamate Dehydrogenase - metabolism Glutamate-Ammonia Ligase - metabolism glutamic acid Glutamic Acid - metabolism Glutaminase - metabolism high protein diet meat messenger RNA Metabolism muscle Muscles - enzymology Muscles - metabolism Muscular system Poultry Proteins taste |
| title | Regulation of muscular glutamate metabolism by high-protein diet in broiler chicks |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T08%3A48%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Regulation%20of%20muscular%20glutamate%20metabolism%20by%20high-protein%20diet%20in%20broiler%20chicks&rft.jtitle=Animal%20science%20journal&rft.au=Kobayashi,%20Hiroyuki&rft.date=2011-02&rft.volume=82&rft.issue=1&rft.spage=86&rft.epage=92&rft.pages=86-92&rft.issn=1344-3941&rft.eissn=1740-0929&rft_id=info:doi/10.1111/j.1740-0929.2010.00811.x&rft_dat=%3Cproquest_cross%3E2250068341%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=847532254&rft_id=info:pmid/21269365&rfr_iscdi=true |