Pulmonary alveolar proteinosis in three infants
Chronic lung disease in children may present a perplexing diagnostic problem. While open lung biopsy usually will provide a diagnosis without excessive morbidity, we believe that pulmonary alveolar proteinosis can be diagnosed radiographically, and we wish to point out the early age at which this di...
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| Veröffentlicht in: | Pediatrics (Evanston) 1968-02, Vol.41 (2), p.510-515 |
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| container_title | Pediatrics (Evanston) |
| container_volume | 41 |
| creator | Wilkinson, R H Blanc, W A Hagstrom, J W |
| description | Chronic lung disease in children may present a perplexing diagnostic problem. While open lung biopsy usually will provide a diagnosis without excessive morbidity, we believe that pulmonary alveolar proteinosis can be diagnosed radiographically, and we wish to point out the early age at which this disease can occur.
The clinical course of three infants is described together with the necropsy findings. Two 3-month-old and one 23-month-old infants are reported. The radiographic appearance of diffuse alveolar consolidation and the progressive respiratory involvement should alert physicians to the true nature of this disease. Recovery is reported in adults, but results of treatment in infants is disappointing. |
| doi_str_mv | 10.1542/peds.41.2.510 |
| format | Article |
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The clinical course of three infants is described together with the necropsy findings. Two 3-month-old and one 23-month-old infants are reported. The radiographic appearance of diffuse alveolar consolidation and the progressive respiratory involvement should alert physicians to the true nature of this disease. Recovery is reported in adults, but results of treatment in infants is disappointing.</description><identifier>ISSN: 0031-4005</identifier><identifier>EISSN: 1098-4275</identifier><identifier>DOI: 10.1542/peds.41.2.510</identifier><identifier>PMID: 5639205</identifier><language>eng</language><publisher>United States</publisher><subject>Child, Preschool ; Female ; Humans ; Infant ; Male ; Pulmonary Alveolar Proteinosis - diagnostic imaging ; Pulmonary Alveolar Proteinosis - pathology ; Pulmonary Alveolar Proteinosis - physiopathology ; Pulmonary Alveolar Proteinosis - therapy ; Radiography</subject><ispartof>Pediatrics (Evanston), 1968-02, Vol.41 (2), p.510-515</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c288t-ba62543f422489b01a16b75ace28e93bca890d127983699f056b462b18571f093</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5639205$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wilkinson, R H</creatorcontrib><creatorcontrib>Blanc, W A</creatorcontrib><creatorcontrib>Hagstrom, J W</creatorcontrib><title>Pulmonary alveolar proteinosis in three infants</title><title>Pediatrics (Evanston)</title><addtitle>Pediatrics</addtitle><description>Chronic lung disease in children may present a perplexing diagnostic problem. While open lung biopsy usually will provide a diagnosis without excessive morbidity, we believe that pulmonary alveolar proteinosis can be diagnosed radiographically, and we wish to point out the early age at which this disease can occur.
The clinical course of three infants is described together with the necropsy findings. Two 3-month-old and one 23-month-old infants are reported. The radiographic appearance of diffuse alveolar consolidation and the progressive respiratory involvement should alert physicians to the true nature of this disease. Recovery is reported in adults, but results of treatment in infants is disappointing.</description><subject>Child, Preschool</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Male</subject><subject>Pulmonary Alveolar Proteinosis - diagnostic imaging</subject><subject>Pulmonary Alveolar Proteinosis - pathology</subject><subject>Pulmonary Alveolar Proteinosis - physiopathology</subject><subject>Pulmonary Alveolar Proteinosis - therapy</subject><subject>Radiography</subject><issn>0031-4005</issn><issn>1098-4275</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1968</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kL9PwzAQhS0EKqUwMiJlYkt6d7YTe0QVBaRKMMBs2akjgvKj2AkS_z2pGjHdGz49vfsYu0XIUApaH_w-ZgIzyiTCGVsiaJUKKuQ5WwJwTAWAvGRXMX4BgJAFLdhC5lwTyCVbv41N23c2_Ca2-fF9Y0NyCP3g666PdUzqLhk-g_dTqGw3xGt2Udkm-pv5rtjH9vF985zuXp9eNg-7tCSlhtTZnKTglSASSjtAi7krpC09Ka-5K63SsEcqtOK51hXI3ImcHCpZYAWar9j9qXca8z36OJi2jqVvGtv5foxGCQWSFE5gegLL0McYfGUOoW6nfwyCOQoyR0FGoCEzCZr4u7l4dK3f_9OzEf4HDg9gGg</recordid><startdate>196802</startdate><enddate>196802</enddate><creator>Wilkinson, R H</creator><creator>Blanc, W A</creator><creator>Hagstrom, J W</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196802</creationdate><title>Pulmonary alveolar proteinosis in three infants</title><author>Wilkinson, R H ; Blanc, W A ; Hagstrom, J W</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c288t-ba62543f422489b01a16b75ace28e93bca890d127983699f056b462b18571f093</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1968</creationdate><topic>Child, Preschool</topic><topic>Female</topic><topic>Humans</topic><topic>Infant</topic><topic>Male</topic><topic>Pulmonary Alveolar Proteinosis - diagnostic imaging</topic><topic>Pulmonary Alveolar Proteinosis - pathology</topic><topic>Pulmonary Alveolar Proteinosis - physiopathology</topic><topic>Pulmonary Alveolar Proteinosis - therapy</topic><topic>Radiography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wilkinson, R H</creatorcontrib><creatorcontrib>Blanc, W A</creatorcontrib><creatorcontrib>Hagstrom, J W</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatrics (Evanston)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wilkinson, R H</au><au>Blanc, W A</au><au>Hagstrom, J W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pulmonary alveolar proteinosis in three infants</atitle><jtitle>Pediatrics (Evanston)</jtitle><addtitle>Pediatrics</addtitle><date>1968-02</date><risdate>1968</risdate><volume>41</volume><issue>2</issue><spage>510</spage><epage>515</epage><pages>510-515</pages><issn>0031-4005</issn><eissn>1098-4275</eissn><abstract>Chronic lung disease in children may present a perplexing diagnostic problem. While open lung biopsy usually will provide a diagnosis without excessive morbidity, we believe that pulmonary alveolar proteinosis can be diagnosed radiographically, and we wish to point out the early age at which this disease can occur.
The clinical course of three infants is described together with the necropsy findings. Two 3-month-old and one 23-month-old infants are reported. The radiographic appearance of diffuse alveolar consolidation and the progressive respiratory involvement should alert physicians to the true nature of this disease. Recovery is reported in adults, but results of treatment in infants is disappointing.</abstract><cop>United States</cop><pmid>5639205</pmid><doi>10.1542/peds.41.2.510</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | Pediatrics (Evanston), 1968-02, Vol.41 (2), p.510-515 |
| issn | 0031-4005 1098-4275 |
| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Child, Preschool Female Humans Infant Male Pulmonary Alveolar Proteinosis - diagnostic imaging Pulmonary Alveolar Proteinosis - pathology Pulmonary Alveolar Proteinosis - physiopathology Pulmonary Alveolar Proteinosis - therapy Radiography |
| title | Pulmonary alveolar proteinosis in three infants |
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