Evidence for a genetic factor related to leukemogenesis and congenital anomalies: Chromosomal aberrations in pedigree of an infant with partial D trisomy and leukemia

Chromosomal studies of relatives of an infant with myeloblastic leukemia and clinical and cytogenetic findings consistent with partial D 1 trisomy showed excessive breakage, chromatid exchange and endoreduplication, and fragment formation in 3 generations of the pedigree, which suggests a genetic fa...

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Veröffentlicht in:	The Journal of pediatrics 1968-01, Vol.72 (3), p.367-376
Hauptverfasser:	Zuelzer, Wolf W., Thompson, Ruby I., Mastrangelo, Renato
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Bone Marrow Cells Chromosomes, Human, 13-15 Chromosomes, Human, 6-12 and X Cleft Lip - genetics Female Humans Infant Karyotyping Leukemia, Myeloid, Acute - genetics Leukocytes Male Middle Aged Pedigree Trisomy
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