Tritiated digoxin. XIV. Enterohepatic circulation, absorption, and excretion studies in human volunteers

Metabolic turnover studies performed on six patients with surgically induced biliary fistula given tritiated digoxin reveal virtually all stool excretion of digoxin to be derived from bile. This establishes the relative lack of recycling of digoxin as an important factor in digoxin metabolism. This...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 1970-11, Vol.42 (5), p.867-873
Hauptverfasser:	Doherty, J E, Flanigan, W J, Murphy, M L, Bulloch, R T, Dalrymple, G L, Beard, O W, Perkins, W H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Bile - analysis Biliary Tract Diseases - surgery Binding Sites Chromatography, Thin Layer Digoxin - metabolism Drainage Humans Intestinal Absorption Liver - metabolism Liver Circulation Male Middle Aged Tritium
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