Deletion of competence-induced genes over-expressed in biofilms caused transformation deficiencies in Streptococcus mutans

Summary Previous studies identified nine genes with increased expression in Streptococcus mutans biofilms of which six possessed putative ComX promoter sequences and were homologous to competence‐induced genes in Streptococcus pneumoniae, Streptococcus gordonii and Bacillus subtilis. As competence i...

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Veröffentlicht in:	Molecular oral microbiology 2010-12, Vol.25 (6), p.406-417
Hauptverfasser:	Eaton, R.E., Jacques, N.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacillus subtilis Bacillus subtilis - genetics Bacterial Proteins - genetics Bacteriology Biofilms Biological and medical sciences Choline-binding protein Chromosome deletion Chromosomes, Bacterial - genetics cin-box competence Conserved Sequence - genetics Deletion mutant Dentistry Deoxyribonucleases, Type II Site-Specific - genetics DNA-Binding Proteins - genetics Enzymes Escherichia coli - genetics Fundamental and applied biological sciences. Psychology Gene Deletion Gene Expression Regulation, Bacterial - genetics Homology Humans Membrane Proteins - genetics Microbiology Miscellaneous Mutation - genetics N-Acetylmuramoyl-L-alanine Amidase - genetics peptidoglycan degrading enzyme peptidoglycan hydrolase Plasmids Plasmids - genetics Promoters Quorum Sensing - genetics Rec A Recombinases - genetics RecA protein recombinase Sequence Homology, Nucleic Acid single-stranded DNA-binding protein Streptococcus gordonii Streptococcus mutans Streptococcus mutans - genetics Streptococcus mutans - physiology Streptococcus pneumoniae Streptococcus pneumoniae - genetics Transcription Factors - genetics Transformation Transformation, Bacterial - genetics
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