Genetic alterations of the LKB1 gene in head and neck cancer

The genetic alterations associated with head and neck cancer (HNC) are numerous and include a variety of different pathways. It has also been shown that numerous tumor suppressor genes are involved in HNC. The LKB1 gene has been defined as a tumor suppressor gene, and somatic mutations of this gene...

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Veröffentlicht in:	DNA and cell biology 2010-12, Vol.29 (12), p.735-738
Hauptverfasser:	Kenanli, Ebru, Karaman, Emin, Enver, Ozgun, Ulutin, Turgut, Buyru, Nur
Format:	Artikel
Sprache:	eng
Schlagworte:	Carcinoma, Squamous Cell - genetics Exons - genetics Female Head and Neck Neoplasms - genetics Humans Male Middle Aged Mutation, Missense Nuclear Localization Signals - genetics Point Mutation Protein-Serine-Threonine Kinases - genetics
Online-Zugang:	Volltext
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