Natural killer cell activation in mice and men: different triggers for similar weapons?

The signaling pathways that regulate B and T lymphocytes are remarkably conserved between humans and mice. However, recent evidence suggests that the pathways regulating natural killer (NK) cell activation may actually differ between these two species. We discuss the controversies in the field and p...

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Veröffentlicht in:	Nature immunology 2002-09, Vol.3 (9), p.807-813
Hauptverfasser:	Colucci, Francesco, Di Santo, James P., Leibson, Paul J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine Cytotoxicity, Immunologic Humans Immunology Infectious Diseases Killer Cells, Natural - immunology Lymphocyte Activation Lymphocytes Mice review-article Species Specificity
Online-Zugang:	Volltext
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