High expression of 67-kDa laminin receptor relates to the proliferation of leukemia cells and increases expression of GM-CSF receptor

Objective The 67-kDa laminin receptor (LR) is a nonintegrin receptor for laminin, a major component of the extracellular matrix. To elucidate the role of LR in leukemia cells, we studied the relationship between the phenotype of leukemia cells and LR expression. Materials and Methods The relationshi...

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Veröffentlicht in:	Experimental hematology 2011-02, Vol.39 (2), p.179-186.e4
Hauptverfasser:	Ando, Koji, Miyazaki, Yasushi, Sawayama, Yasushi, Tominaga, Shinya, Matsuo, Emi, Yamasaki, Reishi, Inoue, Yoriko, Iwanaga, Masako, Imanishi, Daisuke, Tsushima, Hideki, Fukushima, Takuya, Imaizumi, Yoshitaka, Taguchi, Jun, Yoshida, Shinichiro, Hata, Tomoko, Tomonaga, Masao
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Apoptosis - physiology Cell Proliferation Gene Expression Regulation, Neoplastic Hematology, Oncology and Palliative Medicine Humans Leukemia, Myeloid, Acute - blood Leukemia, Myeloid, Acute - physiopathology Phosphorylation Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - metabolism Receptors, Laminin - metabolism STAT5 Transcription Factor - metabolism Tumor Cells, Cultured
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