Trimetazidine: a meta-analysis of randomised controlled trials in heart failure

ObjectiveTo explore whether trimetazidine could improve symptoms, cardiac functions and clinical outcomes in patients with heart failure (HF).MethodsA systematic literature search was conducted to identify randomised controlled trials (RCT) of trimetazidine for HF between 1966 and May 2010 in Pubmed...

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Veröffentlicht in:	Heart (British Cardiac Society) 2011-02, Vol.97 (4), p.278-286
Hauptverfasser:	Gao, Dengfeng, Ning, Ning, Niu, Xiaolin, Hao, Guanghua, Meng, Zhe
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetyl-CoA C-Acyltransferase - antagonists & inhibitors Adult Biological and medical sciences Cardiology Cardiology. Vascular system Chronic Disease Classification Clinical trials Enzyme Inhibitors - therapeutic use Exercise Tolerance Heart Heart attacks Heart failure Heart Failure - drug therapy Heart Failure - physiopathology Heart failure, cardiogenic pulmonary edema, cardiac enlargement Humans Medical sciences Meta-analysis Metabolism Mortality Oxidation Patients Quality Randomized Controlled Trials as Topic Statistical analysis Stroke Volume - drug effects Studies Treatment Outcome Trimetazidine - therapeutic use Validity Vasodilator Agents - therapeutic use Ventricular Remodeling
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