The microtubule inhibiting agent epothilone B antagonizes glioma cell motility associated with reorganization of the actin-binding protein α-actinin 4

Invasion of normal brain tissue by brain tumor cells is a major contributing factor to the recurrence and resistance of clinically diagnosed glioblastomas to therapy (surgery, chemotherapy, radiation). Here, we have assessed the efficacy of the microtubule inhibiting agent epothilone B on glioblasto...

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Veröffentlicht in:Oncology reports 2011-03, Vol.25 (3), p.887-893
Hauptverfasser: HENRY, Whitney I, DUBOIS, Juwen, QUICK, Quincy A
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Sprache:eng
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