A multiresistance megaplasmid pLG1 bearing a hylEfm genomic island in hospital Enterococcus faecium isolates

Enterococcus faecium is considered to be a nosocomial pathogen with increasing medical importance. The putative virulence factor, hyl(Efm), encoding a putative hyaluronidase, is enriched among the hospital-associated polyclonal subpopulation of E. faecium.. The hyl(Efm) gene is described to be part...

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Veröffentlicht in:	International journal of medical microbiology 2011-02, Vol.301 (2), p.165-175
Hauptverfasser:	Laverde Gomez, Jenny A, van Schaik, Willem, Freitas, Ana R, Coque, Teresa M, Weaver, Keith E, Francia, Maria Victoria, Witte, Wolfgang, Werner, Guido
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Bacterial Proteins - genetics Conjugation, Genetic Conserved Sequence Cross Infection - microbiology DNA, Bacterial - chemistry DNA, Bacterial - genetics Drug Resistance, Multiple, Bacterial Enterococcus faecalis - genetics Enterococcus faecium - drug effects Enterococcus faecium - genetics Enterococcus faecium - isolation & purification Enterococcus faecium - pathogenicity Gene Transfer, Horizontal Genomic Islands Gram-Positive Bacterial Infections - microbiology Humans Molecular Sequence Data Plasmids - analysis Sequence Analysis, DNA Virulence Factors - genetics
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