RAD51 135G/C polymorphism and breast cancer risk: a meta-analysis from 21 studies

Growing evidence suggests that RAD51 plays a pivotal role in the repair of DNA double-strand breaks and the maintenance of genomic stability. A single nucleotide polymorphism, 135G/C, has been identified in the 5′ untranslated region of the RAD51 gene and has been shown to influence gene transcripti...

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Veröffentlicht in:	Breast cancer research and treatment 2011-02, Vol.125 (3), p.827-835
Hauptverfasser:	Gao, Lin-Bo, Pan, Xin-Min, Li, Li-Juan, Liang, Wei-Bo, Zhu, Yi, Zhang, Lu-Shun, Wei, Yong-Gang, Tang, Ming, Zhang, Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	5' Untranslated Regions Biological and medical sciences Breast cancer breast neoplasms Breast Neoplasms - genetics Cancer Cancer research Case-Control Studies DNA DNA Repair Epidemiology Genes Genetic aspects Genetic Markers Genetic Predisposition to Disease Genetic transcription Genotype Gynecology. Andrology. Obstetrics Health aspects Humans Mammary gland diseases Medical sciences Medicine Medicine & Public Health Meta-analysis Models, Genetic Mutation Oncology Oncology, Experimental Polymorphism Polymorphism, Genetic Polymorphism, Single Nucleotide RAD51 Rad51 Recombinase - genetics Risk Risk Factors single nucleotide polymorphism Tumors
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