One-Pot Tandem Copper-Catalyzed Library Synthesis of 1-Thiazolyl-1,2,3-triazoles as Anticancer Agents

One-pot multicomponent synthesis to assemble compounds has been an efficient method for constructing a compound library. We have developed one-pot tandem copper-catalyzed azidation and CuAAC reactions that afford 1-thiazolyl-1,2,3-triazoles with anticancer activity. By utilizing this one-pot synthet...

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Veröffentlicht in:	ACS combinatorial science 2011-01, Vol.13 (1), p.72-78
Hauptverfasser:	Li, Wen-Tai, Wu, Wan-Hsun, Tang, Chien-Hsiang, Tai, Ready, Chen, Shui-Tein
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - chemical synthesis Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Catalysis Copper - chemistry Fluorescence Microscopy, Electron, Scanning Triazoles - chemical synthesis Triazoles - chemistry Triazoles - pharmacology
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