Simple Three-Component Method for the Synthesis of Spiroindeno[1,2-b]pyrido[2,3-d]pyrimidine-5,3′-indolines
An efficient, simple, and catalyst-free synthesis of spiroindeno[1,2-b]pyrido[2,3-d]pyrimidine-5,3′-indolines and spiroacenaphthylene-1,4′-indeno-1,5′-pyrido[2,3-d]pyrimidines by the three-component reaction of 1,3-indandione, amino uracils and isatins or acenaphthylene-1,2-dione in refluxing ethano...
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Veröffentlicht in: | ACS combinatorial science 2011-01, Vol.13 (1), p.96-99 |
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creator | Imani Shakibaei, Ghazaleh Feiz, Afsaneh Reza Khavasi, Hamid Abolhasani Soorki, Ali Bazgir, Ayoob |
description | An efficient, simple, and catalyst-free synthesis of spiroindeno[1,2-b]pyrido[2,3-d]pyrimidine-5,3′-indolines and spiroacenaphthylene-1,4′-indeno-1,5′-pyrido[2,3-d]pyrimidines by the three-component reaction of 1,3-indandione, amino uracils and isatins or acenaphthylene-1,2-dione in refluxing ethanol is reported. |
doi_str_mv | 10.1021/co1000053 |
format | Article |
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subjects | Indoles - chemical synthesis Indoles - pharmacology Microbial Sensitivity Tests Models, Molecular |
title | Simple Three-Component Method for the Synthesis of Spiroindeno[1,2-b]pyrido[2,3-d]pyrimidine-5,3′-indolines |
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