Cells of origin in cancer

Both solid tumours and leukaemias show considerable histological and functional heterogeneity. It is widely accepted that genetic lesions have a major role in determining tumour phenotype, but evidence is also accumulating that cancers of distinct subtypes within an organ may derive from different &...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 2011-01, Vol.469 (7330), p.314-322
1. Verfasser:	Visvader, Jane E.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/71 692/700/139 692/700/565/1436/1983 Animals Biological and medical sciences Cancer Carcinogenesis, carcinogens and anticarcinogens Cell Lineage Cells Development and progression DNA repair Epigenetics General aspects Genetic aspects Genotype & phenotype Hematologic Neoplasms - pathology Heterogeneity Humanities and Social Sciences Humans Leukemia Medical sciences Models, Biological multidisciplinary Mutation Neoplasms - diagnosis Neoplasms - genetics Neoplasms - pathology Neoplasms - therapy Neoplastic Stem Cells - pathology Phenotype review-article Science Science (multidisciplinary) Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!