Experimental Feline Infectious Enteritis in the Germfree Cat: An Electron Microscopic Study
Selected tissues from 13 germfree and 3 specific pathogen-free cats experimentally infected with feline infectious enteritis were studied electron microscopically. Intestinal lesions consisting of dilatation of intercellular spaces and of endoplasmic reticular cisternae occurred only in specific pat...
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| Veröffentlicht in: | Pathologia veterinaria 1967, Vol.4 (3), p.275-288 |
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| container_title | Pathologia veterinaria |
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| creator | Johnson, G. R. Koestner, A. Rohovsky, M. W. |
| description | Selected tissues from 13 germfree and 3 specific pathogen-free cats experimentally infected with feline infectious enteritis were studied electron microscopically. Intestinal lesions consisting of dilatation of intercellular spaces and of endoplasmic reticular cisternae occurred only in specific pathogen-free cats. No lesion was demonstrated in the intestine of infected germfree cats, indicating that the virus of feline infectious enteritis may not be solely responsible for the intestinal lesions described in the naturally occurring disease. The lesions in the lymph nodes were identical in specific pathogen-free and germfree cats and consisted of lymphocytic destruction within 72 hours post-inoculation and reactive proliferation of reticular cell-macrophages and plasma cells. The preferred designation of this disease in cats as feline infectious panleukopenia is supported. |
| doi_str_mv | 10.1177/030098586700400307 |
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R. ; Koestner, A. ; Rohovsky, M. W.</creator><creatorcontrib>Johnson, G. R. ; Koestner, A. ; Rohovsky, M. W.</creatorcontrib><description>Selected tissues from 13 germfree and 3 specific pathogen-free cats experimentally infected with feline infectious enteritis were studied electron microscopically. Intestinal lesions consisting of dilatation of intercellular spaces and of endoplasmic reticular cisternae occurred only in specific pathogen-free cats. No lesion was demonstrated in the intestine of infected germfree cats, indicating that the virus of feline infectious enteritis may not be solely responsible for the intestinal lesions described in the naturally occurring disease. The lesions in the lymph nodes were identical in specific pathogen-free and germfree cats and consisted of lymphocytic destruction within 72 hours post-inoculation and reactive proliferation of reticular cell-macrophages and plasma cells. The preferred designation of this disease in cats as feline infectious panleukopenia is supported.</description><identifier>ISSN: 0031-2975</identifier><identifier>EISSN: 1544-4221</identifier><identifier>DOI: 10.1177/030098586700400307</identifier><identifier>PMID: 6078310</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Animals ; Cat Diseases - pathology ; Cats ; Enteritis - pathology ; Enteritis - veterinary ; Germ-Free Life ; Microscopy, Electron ; Virus Diseases - pathology ; Virus Diseases - veterinary</subject><ispartof>Pathologia veterinaria, 1967, Vol.4 (3), p.275-288</ispartof><rights>1967 American College of Veterinary Pathologists</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c274t-e782d1b2e7fdd2d3d162acfe6dc9ba1d8e2207d21f4ab25411c6024cdf3360ed3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/030098586700400307$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/030098586700400307$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,780,784,4024,21819,27923,27924,27925,43621,43622</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6078310$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Johnson, G. R.</creatorcontrib><creatorcontrib>Koestner, A.</creatorcontrib><creatorcontrib>Rohovsky, M. W.</creatorcontrib><title>Experimental Feline Infectious Enteritis in the Germfree Cat: An Electron Microscopic Study</title><title>Pathologia veterinaria</title><addtitle>Vet Pathol</addtitle><description>Selected tissues from 13 germfree and 3 specific pathogen-free cats experimentally infected with feline infectious enteritis were studied electron microscopically. Intestinal lesions consisting of dilatation of intercellular spaces and of endoplasmic reticular cisternae occurred only in specific pathogen-free cats. No lesion was demonstrated in the intestine of infected germfree cats, indicating that the virus of feline infectious enteritis may not be solely responsible for the intestinal lesions described in the naturally occurring disease. The lesions in the lymph nodes were identical in specific pathogen-free and germfree cats and consisted of lymphocytic destruction within 72 hours post-inoculation and reactive proliferation of reticular cell-macrophages and plasma cells. The preferred designation of this disease in cats as feline infectious panleukopenia is supported.</description><subject>Animals</subject><subject>Cat Diseases - pathology</subject><subject>Cats</subject><subject>Enteritis - pathology</subject><subject>Enteritis - veterinary</subject><subject>Germ-Free Life</subject><subject>Microscopy, Electron</subject><subject>Virus Diseases - pathology</subject><subject>Virus Diseases - veterinary</subject><issn>0031-2975</issn><issn>1544-4221</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1967</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UEtLAzEQDqLUUvsHBGFP3tZOstlkF7xIaWuh4EXPSzaZ6JZ91CQL-u9NafEiOJdh5nsw8xFyS-GBUikXkAGURV4ICcAhTvKCTGnOecoZo5dkGnc0ZaXMr8nc-z3EykrBcj4hEwGyyChMyePq64Cu6bAPqk3W2DY9Jtveog7NMPpk1YcIh8YnTZ-ED0w26DrrEJOlCjfkyqrW4_zcZ-RtvXpdPqe7l812-bRLNZM8pCgLZmjNUFpjmMkMFUxpi8LoslbUFMgYSMOo5aqO91GqBTCujc0yAWiyGbk_-R7c8DmiD1XXeI1tq3qMR1YFFwJ4ISORnYjaDd47tNUh_qbcd0WhOqZW_U0tiu7O7mPdofmVnDOK-OKEe_WO1X4YXR-f_c_xB8jDc-I</recordid><startdate>1967</startdate><enddate>1967</enddate><creator>Johnson, G. R.</creator><creator>Koestner, A.</creator><creator>Rohovsky, M. W.</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1967</creationdate><title>Experimental Feline Infectious Enteritis in the Germfree Cat</title><author>Johnson, G. R. ; Koestner, A. ; Rohovsky, M. W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c274t-e782d1b2e7fdd2d3d162acfe6dc9ba1d8e2207d21f4ab25411c6024cdf3360ed3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1967</creationdate><topic>Animals</topic><topic>Cat Diseases - pathology</topic><topic>Cats</topic><topic>Enteritis - pathology</topic><topic>Enteritis - veterinary</topic><topic>Germ-Free Life</topic><topic>Microscopy, Electron</topic><topic>Virus Diseases - pathology</topic><topic>Virus Diseases - veterinary</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Johnson, G. R.</creatorcontrib><creatorcontrib>Koestner, A.</creatorcontrib><creatorcontrib>Rohovsky, M. W.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Pathologia veterinaria</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Johnson, G. R.</au><au>Koestner, A.</au><au>Rohovsky, M. W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Experimental Feline Infectious Enteritis in the Germfree Cat: An Electron Microscopic Study</atitle><jtitle>Pathologia veterinaria</jtitle><addtitle>Vet Pathol</addtitle><date>1967</date><risdate>1967</risdate><volume>4</volume><issue>3</issue><spage>275</spage><epage>288</epage><pages>275-288</pages><issn>0031-2975</issn><eissn>1544-4221</eissn><abstract>Selected tissues from 13 germfree and 3 specific pathogen-free cats experimentally infected with feline infectious enteritis were studied electron microscopically. Intestinal lesions consisting of dilatation of intercellular spaces and of endoplasmic reticular cisternae occurred only in specific pathogen-free cats. No lesion was demonstrated in the intestine of infected germfree cats, indicating that the virus of feline infectious enteritis may not be solely responsible for the intestinal lesions described in the naturally occurring disease. The lesions in the lymph nodes were identical in specific pathogen-free and germfree cats and consisted of lymphocytic destruction within 72 hours post-inoculation and reactive proliferation of reticular cell-macrophages and plasma cells. The preferred designation of this disease in cats as feline infectious panleukopenia is supported.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>6078310</pmid><doi>10.1177/030098586700400307</doi><tpages>14</tpages></addata></record> |
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| ispartof | Pathologia veterinaria, 1967, Vol.4 (3), p.275-288 |
| issn | 0031-2975 1544-4221 |
| language | eng |
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| source | Access via SAGE; MEDLINE |
| subjects | Animals Cat Diseases - pathology Cats Enteritis - pathology Enteritis - veterinary Germ-Free Life Microscopy, Electron Virus Diseases - pathology Virus Diseases - veterinary |
| title | Experimental Feline Infectious Enteritis in the Germfree Cat: An Electron Microscopic Study |
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